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CC BY 4.0 · Journal of Digestive Endoscopy 2024; 15(01): 18-26
DOI: 10.1055/s-0044-1779617
Research Article

Correlative Factors of Severity of Air Bubbles in the Large Intestine during Colonoscopy

Takaaki Yoshikawa 
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Atsushi Yamauchi
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Kumi Itami
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Shinichiro Odo
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Yoshihiro Soma
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Kosuke Tanaka
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Kazuki Negoro
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Yuki Mori
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Kazuki Osawa
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Ryou Itou
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Yuya Kawai
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Sota Nakagami
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Shunjiro Azuma
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Toshihiro Morita
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Kenshiro Hirohashi
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Katsutoshi Kuriyama
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Ken Takahashi
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Tadayuki Kou
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Toshiro Katayama
2   Help Center of Medical Research, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
,
Shujiro Yazumi 
1   Department of Gastroenterology and Hepatology, Medical Research Institute Kitano Hospital, PIIF Tazuke Kofukai, Ohgimachi, Kita-ku, Osaka, Japan
› Author Affiliations Funding None.
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Abstract

Objectives The condition of air bubbles in the large intestine is an influential factor for good quality of colonoscopy. However, the correlative factors of severity of air bubbles during colonoscopy in the large intestine are not established. Therefore, this study aimed to elucidate the correlative factors influencing the severity of air bubbles in the large intestine.

Materials and Methods A total of 314 examinees who underwent colonoscopy between August and September 2022 were enrolled (median age [range], 65 [18–88] years). Air bubbles were scored using the Colon Endoscopic Bubble Scale (CEBuS) and the clinical factors associated with the CEBuS scores, especially in the ileocecum, were analyzed.

Results In this study, 39.8% (125/314) of examinees harbored severe air bubbles in the ileocecum. Multiple linear regression analysis revealed that the CEBuS scores in the ileocecum were positively associated with the interval time from completion of bowel preparation to intubation of the cecum (p = 0.0016) and a history of cholecystectomy (p = 0.0198). Logistic regression analysis between no, mild, and moderate air bubbles group (n = 189) and severe air bubbles group (n = 125) also showed that severity was positively associated with the interval time from completion of bowel preparation to intubation of the cecum (p = 0.0332) and a history of cholecystectomy (p = 0.0095).

Conclusion Interval time and history of cholecystectomy were associated with severity of air bubbles in the large intestine after bowel preparation.

Keywords

colon - colonoscopy - colorectal polyp - endoscopy

Authors' Contributions

Conceptualization: T.Y., A.Y.; collection of data: K.I., S.O., Y.S., K.Tanaka, K.N.; data analysis: T.Y., A.Y., Y.M., K.O., R.I., Y.K., S.N., S.A., T.M., K.H., K.K., K.Takahashi, T.Kou, T.Katayama, S.Y.; writing-original draft: T.Y.


Ethics Approval

Opt-out informed consent protocol was used for this study. This consent procedure was reviewed and approved by Kitano Hospital (approval No. 2209004).


Data Availability Statement

The datasets generated and analyzed in the current study are available from the corresponding author on reasonable request.


Supplementary Material



Publication History

Article published online:
02 April 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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