CC BY 4.0 · Arch Plast Surg 2024; 51(04): 417-422
DOI: 10.1055/s-0044-1782142
Extremity/Lymphedema
Case Report

LVAs in a Pedicled SIEA Flap for the Treatment of Recurrent Lymphocele of the Groin Using Superficial Veins of the Flap for Lymphovenous Anastomosis: A Case Report and Literature Review

1   Plastic Surgery Unit, San Bortolo Hospital, Vicenza, Vicenza, Italy
,
Elmar Fritsche
2   Department of Hand- and Plastic Surgery, Luzerner Kantonsspital, Lucerne, Switzerland
,
2   Department of Hand- and Plastic Surgery, Luzerner Kantonsspital, Lucerne, Switzerland
› Author Affiliations

Abstract

Persistent lymphocele of the groin is a complication of groin surgery that can severely impact the quality of life. The restoration of the interrupted lymphatic pathway is considered by many authors the ideal treatment to prevent a recurrence. However, multiple aspiration procedures and surgical revisions can compromise the availability of local veins needed for a lymphovenular bypass surgery. In addition, surgical debridement of a long-standing lymphocele can generate extensive dead space and contour deformity. A flap delivering additional venules for trans-flap lymphovenular anastomoses (LVAs) can overcome both problems by providing soft tissue and competent veins harvested outside the zone of injury.

A successful case of severe groin lymphocele treated with trans-flap LVAs from an abdominal-based flap is presented. The patient was referred to us for a recurrent lymphocele developed in the right groin after lipoma excision that persisted despite multiple surgical attempts. After the identification of patent and draining inguinal lymphatic vessels, a pinch test was used to design a mini-abdominoplasty superficial inferior epigastric artery flap. The superficial veins of the cranial incision were identified and anastomosed to the lymphatic vessels after the pedicled flap harvested and insetted in the groin.

The early restoration of lymphatic drainage and the optimal aesthetic outcome supports the combined approach offered by trans-flap LVAs as a valuable therapeutic option for severe and persistent lymphocele.

Authors' Contributions

• Substantial contributions to conception and design, acquisition of data, and analysis and interpretation of data: F.F., A.F.


• Drafting the article or revising it critically for important intellectual content: F.F., A.F.


• Final approval of the version to be published: F.F., A.F., E.F.


• Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: F.F., A.F., E.F.


Ethical Approval

This study was conducted in accordance with the Second Helsinki Declaration.


Patient Consent

The patient signed a written informed consent for the procedure and to be included in the study. The patient is aware that her photographs will be released with the paper.




Publication History

Received: 24 May 2023

Accepted: 29 January 2024

Article published online:
13 June 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Longras C, Figueiredo Braga S, Carrilho C, Mesquita A. Recurrent inguinal lymphocele - a therapeutic challenge. Port J Card Thorac Vasc Surg 2021; 28 (02) 75-76
  • 2 Nicksic PJ, Condit KM, Nayar HS, Michelotti BF. Algorithmic approach to the lymphatic leak after vascular reconstruction: a systematic review. Arch Plast Surg 2021; 48 (04) 404-409
  • 3 Uyulmaz S, Planegger A, Grünherz L, Giovanoli P, Lindenblatt N. Lymphovenous anastomoses and microscopic lymphatic ligations for the treatment of persistent lymphocele. Plast Reconstr Surg Glob Open 2021; 9 (02) e3407
  • 4 Van den Brande P, von Kemp K, Aerden D. et al. Treatment of lymphocutaneous fistulas after vascular procedures of the lower limb: accurate wound reclosure and 3 weeks of consistent and continuing drainage. Ann Vasc Surg 2012; 26 (06) 833-838
  • 5 Smolock AR, Nadolski G, Itkin M. Intranodal glue embolization for the management of postsurgical groin lymphocele and lymphorrhea. J Vasc Interv Radiol 2018; 29 (10) 1462-1465
  • 6 Parrado RH, Thomas CS, Countryman D. Successful treatment of inguinal lymphocele after angiomyomatous hamartoma resection during inguinal hernia repair. Wounds 2021; 33 (07) E42-E45
  • 7 Tashiro K, Arikawa M, Kagaya Y, Kobayashi E, Kawai A, Miyamoto S. Flap reconstruction after groin and medial thigh sarcoma resection reduces the risk of lower-extremity lymphedema. J Plast Reconstr Aesthet Surg 2019; 72 (04) 685-710
  • 8 Mitsui K, Narushima M, Danno K, Ishiura R, Banda CH. Intra-lymphocele microsurgical identification of causative afferent vessels for effective lymphaticovenular anastomosis in lymphocele treatment: a case report. Microsurgery 2024; 44 (01) e31002
  • 9 Scaglioni MF, Meroni M, Fritsche E. Inguinal seroma/lymphocele prevention after superficial circumflex iliac artery perforator (SCIP) flap harvest using the deep branch as donor vein for lymphovenous anastomosis (LVA). Microsurgery 2021; 41 (01) 95-96
  • 10 Gentileschi S, Servillo M, Salgarello M. Supramicrosurgical lymphatic-venous anastomosis for postsurgical subcutaneous lymphocele treatment. Microsurgery 2015; 35 (07) 565-568
  • 11 di Summa PG, Guillier D. The lymphatic flow-through (LyFT) flap: proof of concept of an original approach. J Plast Reconstr Aesthet Surg 2020; 73 (05) 983-1007
  • 12 Scaglioni MF, Meroni M, Fritsche E, Fuchs B. Total groin defect reconstruction by lymphatic flow-through (LyFT) pedicled deep inferior epigastric artery perforator (DIEP) flap resorting to its superficial veins for lymphovenous anastomosis (LVA): a case report. Microsurgery 2022; 42 (02) 170-175
  • 13 Kleinhans E, Baumeister RG, Hahn D, Siuda S, Büll U, Moser E. Evaluation of transport kinetics in lymphoscintigraphy: follow-up study in patients with transplanted lymphatic vessels. Eur J Nucl Med 1985; 10 (7-8): 349-352
  • 14 Suzuki Y, Sakuma H, Yamazaki S, Ihara J. Lymphatic tract reconstruction using a pedicled deep inferior epigastric perforator flap. Lymphology 2018; 51 (02) 79-84
  • 15 Boccardo F, Dessalvi S, Campisi C. et al. Microsurgery for groin lymphocele and lymphedema after oncologic surgery. Microsurgery 2014; 34 (01) 10-13
  • 16 Yamamoto T, Yoshimatsu H, Koshima I. Navigation lymphatic supermicrosurgery for iatrogenic lymphorrhea: supermicrosurgical lymphaticolymphatic anastomosis and lymphaticovenular anastomosis under indocyanine green lymphography navigation. J Plast Reconstr Aesthet Surg 2014; 67 (11) 1573-1579
  • 17 Ayestaray B, Esnault M, Godard M, Picquot S. Treatment of refractory groin lymphocele by surrounding supermicrosurgical lymphaticovenous anastomosis. Arch Plast Surg 2018; 45 (03) 290-291
  • 18 Giacalone G, Yamamoto T, Hayashi A. et al. Lymphatic supermicrosurgery for the treatment of recurrent lymphocele and severe lymphorrhea. Microsurgery 2019; 39 (04) 326-331
  • 19 Shimono A, Sakuma H, Watanabe S, Kono H. Effective combination of lymphatico-venous anastomosis and negative pressure wound therapy for lymphocyst: a case study. J Obstet Gynaecol Res 2020; 46 (07) 1224-1228
  • 20 Gabriele G, Tommasino G, Cascino F. et al. Rare case of giant lymphocele treated with supramicrosurgical approach. . Ann Ital Chir 2020;91:S2239253–X20033198
  • 21 Scaglioni MF, Meroni M, Fritsche E. Lymphovenous anastomosis (LVA) for treatment of iatrogenic lymphocele in the thigh. Microsurgery 2021; 41 (01) 19-25
  • 22 Kadota H, Shimamoto R, Fukushima S. et al. Lymphaticovenular anastomosis for lymph vessel injury in the pelvis and groin. Microsurgery 2021; 41 (05) 421-429
  • 23 Guillier D, Guiotto M, Cherix S, Raffoul W, di Summa PG. Lymphatic flow through (LyFT) ALT flap: an original solution to reconstruct soft tissue loss with lymphatic leakage or lower limb lymphedema. J Plast Surg Hand Surg 2023; 57 (1-6): 216-224
  • 24 Blana A, Denzinger S, Lenhart M, Wieland WF, Ganzer R. Treatment of a recurrent inguinal lymphocele in a penis cancer patient by lymphography and selective ligation of lymphatic vessels. Int J Urol 2007; 14 (05) 450-451
  • 25 Lavie O, Karmeli R, Mansano R, Hallak M, Bornstein J, Abramovici H. Treatment of recurrent inguinal lymphocele by lymphatic leakage mapping and subsequent ligation of lymphatic vessel endings: a case report. Gynecol Oncol 2002; 84 (01) 155-156
  • 26 Singer M, Aliano K, Stavrides S, Davenport T. Lymphatic mapping in the treatment of chronic seroma: a case series. Eplasty 2015; 15: e7
  • 27 Stadelmann WK, Tobin GR. Successful treatment of 19 consecutive groin lymphoceles with the assistance of intraoperative lymphatic mapping. Plast Reconstr Surg 2002; 109 (04) 1274-1280
  • 28 Twine CP, Lane IF, Williams IM. Management of lymphatic fistulas after arterial reconstruction in the groin. Ann Vasc Surg 2013; 27 (08) 1207-1215
  • 29 Pu LL, Jahania MS, Mentzer Jr RM. Successful management of recalcitrant groin lymphorrhoea with the combination of intraoperative lymphatic mapping and muscle flap. J Plast Reconstr Aesthet Surg 2006; 59 (12) 1363-1366
  • 30 Scaglioni MF, Meroni M, Franchi A, Fritsche E. Combined lymphovenous anastomosis and deep inferior epigastric perforator flap with lymphatic tissue preservation for defect reconstruction and lymphedema-lymphocele prevention after medial thigh sarcoma resection: a case report. Microsurgery 2020; 40 (05) 598-603
  • 31 Scaglioni MF, Meroni M, Fritsche E. Soft tissue defect reconstruction and lymphatic complications prevention: the lymphatic flow-through (LyFT) concept. Medicina (Kaunas) 2022; 58 (04) 509
  • 32 Scaglioni MF, Meroni M, Fritsche E, Fuchs B. Combined pedicled superficial circumflex iliac artery perforator (SCIP) flap with lymphatic tissue preservation and lymphovenous anastomosis (LVA) for defect reconstruction and lymphedema-lymphocele prevention in thigh sarcoma surgery: preliminary results. J Surg Oncol 2021; 123 (01) 96-103
  • 33 Scaglioni MF, Meroni M, Fritsche E, Fuchs B. Combined double superficial circumflex iliac artery perforator flap with lymphatic tissue preservation and lymphovenous anastomosis for lymphatic sequelae prevention in thigh defect reconstruction: a case report. Microsurgery 2022; 42 (03) 265-270
  • 34 Scaglioni MF, Meroni M, Fritsche E, Fuchs B. The use of pedicled chimeric superficial circumflex iliac artery perforator (SCIP) flap as lymphatic interpositional flap for deep thigh defect reconstruction: a case report. Microsurgery 2022; 42 (04) 360-365
  • 35 Scaglioni MF, Meroni M, Fritsche E. Pedicled superficial circumflex iliac artery perforator flap combined with lymphovenous anastomosis between the recipient site lymphatic vessels and flap superficial veins for reconstruction of groin/thigh tissue defect and creation of lymph flow-through to reduce lymphatic complications: a report of preliminary results. Microsurgery 2023; 43 (01) 44-50
  • 36 Yamamoto T, Yamamoto N, Kageyama T, Sakai H, Fuse Y, Tsukuura R. Lymph-interpositional-flap transfer (LIFT) based on lymph-axiality concept: Simultaneous soft tissue and lymphatic reconstruction without lymph node transfer or lymphatic anastomosis. J Plast Reconstr Aesthet Surg 2021; 74 (10) 2604-2612