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CC BY 4.0 · Int Arch Otorhinolaryngol 2024; 28(04): e561-e567
DOI: 10.1055/s-0044-1785458
Original Research

Mismatch Negativity in Children with Deficits in Auditory Abilities

Julia Dalcin Pinto 
1   Department of Speech Therapy, Centro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil
,
Déborah Aurélio Temp
1   Department of Speech Therapy, Centro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil
,
Laís Ferreira 
1   Department of Speech Therapy, Centro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil
,
Amália El Hatal de Souza
1   Department of Speech Therapy, Centro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil
,
Michele Vargas Garcia
1   Department of Speech Therapy, Centro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil
,
Adriana Neves de Andrade 
2   Department of Speech Therapy, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil
,
Eliara Pinto Vieira Biaggio
1   Department of Speech Therapy, Centro de Ciências da Saúde, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil
› Institutsangaben Funding The study did not receive any funding.
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Abstract

Introduction Mismatch negativity (MMN) represents a negative component of event-related potentials, which is mentioned by guidelines as an important tool to provide measurable data regarding the functionality of the auditory system in acoustic processing. However, the literature still lacks reliable data that can support the clinical use of this potential in the complementary diagnosis of central auditory processing (CAP) disorder (CAPD).

Objectives To analyze whether MMN assessment might be associated with the CAP behavioral test battery, as well as to assess the effects of auditory ability deficits on MMN responses in the pediatric population.

Methods In total, 45 age-matched children participated in the study. They were submitted to the CAP behavior assessment and to MMN. The children were tested with a combination of speech contrast consisting of acoustic syllables [da] versus [ta], governed by the oddball paradigm.

Results Mismatch negativity did not show a direct association with a single test but with the combination of the four tests used as a behavioral test battery to identify CAPD. The results also indicated that the auditory ability deficits influenced the measurement of MMN latency (p = 0.003*), but not the amplitude (p = 0.857) or the area (p = 0.577).

Conclusion Mismatch negativity was shown to be statistically associated with the battery of tests used to identify deficits in auditory abilities in the studied sample rather than with a single behavioral test. The deficits in auditory abilities were observed in the MMN latency. Mismatch negativity can be used to assess children with CAPD.

Keywords

auditory cortex - central auditory processing - central auditory processing disorder - child - auditory evoked potentials

The * indicates statistical significance.




Publikationsverlauf

Eingereicht: 06. Juli 2023

Angenommen: 16. Januar 2024

Artikel online veröffentlicht:
25. Mai 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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