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CC BY-NC-ND 4.0 · Asian J Neurosurg 2024; 19(02): 270-276
DOI: 10.1055/s-0044-1786689
Research Article

Blood Flow Capacity Assessment of End-to-Side Arterial Anastomosis In Vivo in Rats

Maxim Sergeevich Staroverov 
1   Department of Fundamental Neurosurgery, Pirogov Russian National Research Medical University, Moscow, Russia
2   Federal Center of Brain Research and Neurotechnologies of the FMBA, Department of Neurosurgery, Moscow, Russia
,
Vladimir Victorovich Krylov
1   Department of Fundamental Neurosurgery, Pirogov Russian National Research Medical University, Moscow, Russia
2   Federal Center of Brain Research and Neurotechnologies of the FMBA, Department of Neurosurgery, Moscow, Russia
3   Department of Neurosurgery, Sklifosovsky Scientific Research Institute of Emergency Care, Moscow, Russia
,
Victor Alexandrovich Lukyanchikov
1   Department of Fundamental Neurosurgery, Pirogov Russian National Research Medical University, Moscow, Russia
3   Department of Neurosurgery, Sklifosovsky Scientific Research Institute of Emergency Care, Moscow, Russia
4   Department of Neurosurgery, Research Center of Neurology, Moscow, Russia
,
Egor Andreevich Orlov
5   Dietrich-Bonhoeffer-Klinikum, Klinik Neurochirurgie, Neubrandenburg, Germany
,
Alexey Alexandrovich Veselkov
6   Department of Neurosurgery, Burdenko Neurosurgery Institute, Moscow, Russia
,
Sergey Segreevich Dydykin
7   Department of Topographic Anatomy and Operative Surgery, Sechenov University, Moscow, Russia
,
Vladislav Dmitrievich Shatdler
1   Department of Fundamental Neurosurgery, Pirogov Russian National Research Medical University, Moscow, Russia
› Author Affiliations Funding None.
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Abstract

Introduction The aim of this article was to assess the flow capacity of end-to-side arterial anastomosis depending on the method of its implementation.

Materials and Methods The study was conducted on 30 live Wistar rats in vivo, which were randomly divided into three groups. In each group of animals, an end-to-side microanastamosis was performed using three methods of donor artery preparation: 45 degrees (group A), 90 degrees (group B), and arteriotomy according to the “fish mouth” type (group C). The determination of flow capacity of anastomosis by measuring the blood volume flow with transonic flowmeter was performed.

Results The obtained average values after the anastomosis were, respectively, 7.335 mL/s (standard deviation [SD]: 2.0771; min: 4.05; max: 10.85), 7.36 mL/s (SD: 0.836 mi: 6.15; max: 8.75), and 6.37 mL/s (SD: 1.247; min: 5.05; max: 9.05). No statistically significant difference in the blood volume flow velocity between all types of anastomoses was obtained (p = 0.251).

Conclusion The flow capacity of end-to-side arterial anastomosis does not depend on the chosen method of anastomosis.

Keywords

flow capacity of end-to-side arterial anastomosis - blood volume flow velocity - cerebral revascularization - arteriotomy in end-to-side anastomosis - end-to-side anastomosis

Note

All experiments were performed according to the main ethical principles of biomedical experiments on animals, as well as the rules of the Sechenov First Moscow State Medical University Ethics Committee.


Authors' Contributions

V.V.K. and S.S.D contributed to the editing of manuscript. V.A.L. designed the study. M.S.S. and E.A.O. conducted the experiment and helped in literature review. A.A.V. and V.D.S. helped in conducting the experiment.


Ethical Approval

All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.




Publication History

Article published online:
06 June 2024

© 2024. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Yaşargil MG. Microsurgery: Applied to Neurosurgery. St. Louis: Elsevier Science; 2014
    Google Scholar
  • 2 Arnone GD, Hage ZA, Charbel FT. Side-to-side and end-to-side double anastomosis using the parietal-branch of the superficial temporal artery-a novel technique for extracranial to intracranial bypass surgery: 3-dimensional operative video. Oper Neurosurg (Hagerstown) 2019; 16 (01) 112-114
    CrossrefPubMedGoogle Scholar
  • 3 Fossati E, Asurey N, Irigaray A. Application of Kunlin's technique in vascular micro-anastomosis: experimental and clinical study. Microsurgery 1985; 6 (01) 53-55
    CrossrefPubMedGoogle Scholar
  • 4 Harashina T, Irigaray A. Expansion of smaller vessel diameter by fish-mouth incision in microvascular anastomosis with marked size discrepancy. Plast Reconstr Surg 1980; 65 (04) 502-503
    CrossrefPubMedGoogle Scholar
  • 5 Lawton MT, Lang MJ. The future of open vascular neurosurgery: perspectives on cavernous malformations, AVMs, and bypasses for complex aneurysms. J Neurosurg 2019; 130 (05) 1409-1425
    CrossrefPubMedGoogle Scholar
  • 6 López-Monjardin H, de la Peña-Salcedo JA. Techniques for management of size discrepancies in microvascular anastomosis. Microsurgery 2000; 20 (04) 162-166
    CrossrefPubMedGoogle Scholar
  • 7 de la Peña-Salcedo JA, Cuesy C, López-Monjardin H. Experimental microvascular sleeve anastomosis in size discrepancy vessels. Microsurgery 2000; 20 (04) 173-175
    CrossrefPubMedGoogle Scholar
  • 8 Abdulrauf SI. Cerebral Revascularization: Techniques in Extracranial-to-Intracranial Bypass Surgery. Philadelphia, PA: Elsevier Saunders; 2011
    Google Scholar
  • 9 Ueda K, Harashina T, Inoue T, Kurihara T, Harada T, Oba S. Microarterial anastomosis with a distal tapering technique. J Reconstr Microsurg 1994; 10 (02) 87-90
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 Wessels L, Hecht N, Vajkoczy P. Bypass in neurosurgery-indications and techniques. Neurosurg Rev 2019; 42 (02) 389-393
    CrossrefPubMedGoogle Scholar
  • 11 Xiu Z-F, Song Y-G. A new technique to anastomose vessels with great discrepancy in diameter. Br J Plast Surg 1993; 46 (07) 619-620
    CrossrefPubMedGoogle Scholar
  • 12 Thines L, Petyt G, Aguettaz P. et al. Surgical management of Moyamoya disease and syndrome: current concepts and personal experience. Rev Neurol (Paris) 2015; 171 (01) 31-44
    CrossrefPubMedGoogle Scholar
  • 13 Wolfswinkel EM, Landau MJ, Ravina K, Kokot NC, Russin JJ, Carey JN. EC-IC bypass for cerebral revascularization following skull base tumor resection: current practices and innovations. J Surg Oncol 2018; 118 (05) 815-825
    CrossrefPubMedGoogle Scholar
  • 14 Amin-Hanjani S, Du X, Mlinarevich N, Meglio G, Zhao M, Charbel FT. The cut flow index: an intraoperative predictor of the success of extracranial-intracranial bypass for occlusive cerebrovascular disease. Neurosurgery 2005; 56 (1, suppl): 75-85
    PubMedGoogle Scholar