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CC BY-NC-ND 4.0 · International Journal of Practical Otolaryngology 2024; 07(01): e16-e20
DOI: 10.1055/s-0044-1786800
Original Article

Background Factors Associated with Postoperative Complications in Patients with Advanced Hypopharyngeal Cancers Undergoing Total Pharyngolaryngoesophagectomy Followed by Free Jejunal Flap Reconstruction

Shintaro Fujimura
1   Department of Otorhinolaryngology – Head and Neck Surgery, University of Occupational and Environmental Health, Japan
,
Hideaki Suzuki
1   Department of Otorhinolaryngology – Head and Neck Surgery, University of Occupational and Environmental Health, Japan
,
Jun-ichi Ohkubo
1   Department of Otorhinolaryngology – Head and Neck Surgery, University of Occupational and Environmental Health, Japan
,
Ryusuke Hori
1   Department of Otorhinolaryngology – Head and Neck Surgery, University of Occupational and Environmental Health, Japan
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Abstract

We retrospectively analyzed background factors associated with postoperative complications in patients with advanced hypopharyngeal cancers who underwent total pharyngolaryngectomy followed by free jejunal flap reconstruction. A total of 23 participants, including 21 men and 2 women aged 49 to 83 years (average 72.3 years) were enrolled in this study. Mild and moderate/severe complications occurred in five and seven cases, respectively. The most common complication was stricture of the esophagojejunal anastomosis (nine cases). Other complications included two tracheostomal stenosis, one each for pneumonia and chyle leakage. The free jejunal flap survived in all cases. The disease-free survival rate was 47.8% at 52 weeks after surgery. The platelet count was significantly lower (18.8 ± 1.9 × 104/mL vs. 27.7 ± 1.8 × 104/mL; p = 0.008) in patients with moderate/severe complications than in those without. The percentage of stage IV cases and intraoperative blood loss tended to be higher in patients with complications than in those without. Knowledge of these potential risk factors for the development of postoperative complications to satisfactorily manage the clinical course of patients with advanced hypopharyngeal cancers is necessary.

Keywords

hypopharyngeal cancer - total pharyngolaryngectomy - postoperative complication - stricture of the esophagojejunal anastomosis - background factor


Publication History

Received: 22 September 2023

Accepted: 18 January 2024

Article published online:
23 May 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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