Open Access
CC BY-NC-ND 4.0 · Ibnosina Journal of Medicine and Biomedical Sciences 2024; 16(03): 100-107
DOI: 10.1055/s-0044-1787110
Original Article

Exploring the Association between Benign Anorectal Conditions and Colorectal Cancer from the Analysis of Lower Gastrointestinal Endoscopies

1   Department of General Surgery, University of Health Sciences, Umraniye Education and Research Hospital, Istanbul, Türkiye
,
Yahya Kemal Çalışkan
2   Department of General Surgery, University of Health Sciences, Kanuni Education and Research Hospital, Istanbul, Türkiye
,
3   Department of Family Medicine, Family Medicine, Abdulkadir Yüksel State Hospital, Şahinbey, Gaziantep, Türkiye
› Institutsangaben

Funding and Sponsorship None.
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Abstract

Objective Patients experiencing hemorrhoids or fissures may overlook other gastrointestinal (GI) symptoms, assuming that they are linked solely to their existing condition. However, colon cancer, often asymptomatic, can coincide with benign pathologies detected during colonoscopy. This study investigates the prevalence of colorectal cancer (CRC) in patients undergoing lower GI endoscopy for hemorrhoids and elucidates the correlation between cancer and benign pathologies identified during colonoscopy. Highlighting its potential to reveal hidden cancers emphasizes the critical role of colonoscopy in comprehensive health care.

Methods The primary objective was to thoroughly investigate the prevalence of CRC in patients who underwent lower GI endoscopy for hemorrhoids. A comprehensive analysis was conducted using a dataset spanning 7 years of lower GI endoscopy. The main focus of this investigation was to determine the incidence of cancer. Additionally, a meticulous examination of accompanying benign diagnoses was performed to provide a comprehensive evaluation.

Results The study cohort, comprising 6,268 patients, revealed a noteworthy coexistence of malignancies with common conditions. The revelation was of paramount significance that the total number of malignant cases within this cohort was 440. Polyps emerged as the most frequently observed condition, constituting 55.2% (n = 243) of the cases. Diverticulosis was present in 6.6% (n: 29) of cases, while ulcerative colitis was detected in 8% (n: 2) of cases. Hemorrhoids were identified in 20.7% (n: 91) of cases. The findings indicated a substantial association between these common conditions and malignancy. Specifically, it was discovered that approximately 1 in 22 individuals with hemorrhoids, 1 in 52 individuals with fissures, and 1 in 5.7 individuals with polyps were diagnosed with malignancy.

Conclusion This study highlights the pivotal role of colonoscopy in uncovering hidden cancers, especially in patients with hemorrhoids. The findings emphasize the significance of doctors and patients prioritizing colonoscopy, as it allows for early detection and intervention for potential malignancies, even in the presence of hemorrhoids.

Authors' Contributions

FB worked on Conceptualization, Methodology, Software, Writing. YKÇ, YBA looked into Visualization, Investigation, Supervision. Software, Validation, Writing- Reviewing and Editing. All authors contributed to study design.


Compliance with Ethical Principles

This retrospective chart review study with human participants adhered to the ethical standards of the institutional research committee and the 1964 Declaration of Helsinki and its subsequent amendments or comparable ethical standards. All patients and/or their patients and/or guardians signed a general consent form allowing anonymous use of data for education, research, and quality improvement. The authors confirmed that the data were collected anonymously.


Supplementary Material



Publikationsverlauf

Artikel online veröffentlicht:
04. Juni 2024

© 2024. The Libyan Biotechnology Research Center. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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