CC BY 4.0 · Chinese medicine and natural products 2024; 04(02): e66-e75
DOI: 10.1055/s-0044-1787118
Original Article

Comparison of Freeze-Drying and Hot-Air Drying on the Appearance, Microscopic Characterization, and Ginsenosides Contents of the American Ginseng

Qi Liang
1   State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
,
Lin He
2   Sichuan Institute for Drug Control (Sichuan Testing Center of Medical Devices), Chengdu, Sichuan, China
,
Qingqing Tian
3   Sichuan Huotai Pharmaceutical Co., Ltd, Chengdu, Sichuan, China
,
Dong Ran
1   State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
,
Hua Tao
3   Sichuan Huotai Pharmaceutical Co., Ltd, Chengdu, Sichuan, China
,
Qinwan Huang
1   State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
,
Qing Zhang
4   Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States
,
Chunjie Wu
1   State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
,
Wei Peng
1   State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
› Institutsangaben
Funding This work was supported by the Sichuan Huotai Pharmaceutical Co., Ltd under Grant (20200601-1).


Abstract

Purpose Our purpose was to compare the difference between hot-air dried American ginseng (HDAG) (Panacis Quinquefolii Radix) and freeze-dried American ginseng (FDAG) (Panacis Quinquefolii Radix) and provide a better drying approach for improving the quality of American ginseng (Panacis Quinquefolii Radix).

Methods In our present study, we compared the appearance features of HDAG and FDAG using a CR-410 colorimeter and scanning electron microscopy. Furthermore, we qualitatively and quantitatively determined ginsenosides in HDAG and FDAG by using UPLC-Q Exactive Orbitrap-MS/MS and high-performance liquid chromatography.

Results Our present results showed that compared to the hot-air drying method, freeze-drying (FD) has obvious advantages in not only good appearances but also higher bioactive constituents for drying the American ginseng (Panacis Quinquefolii Radix).

Conclusion FD is beneficial for the retention of ginsenosides in American ginseng (Panacis Quinquefolii Radix) and also helpful for maintaining the bioactive effects of this functional food.

CRediT Authorship Contribution Statement

Qi Liang and Lin He: Writing–original draft, methodology, and investigation. Qingqing Tian: Data curation, and methodology. Dong Ran: Investigation, software. Hua Tao: Conceptualization. Qinwan Huang and Qing Zhang: Investigation. Chunjie Wu: Methodology, investigation, supervision, and data curation. Wei Peng: Funding acquisition, writing–review and editing, and supervision.




Publikationsverlauf

Eingereicht: 12. Januar 2024

Angenommen: 20. März 2024

Artikel online veröffentlicht:
27. Juni 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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