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CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2024; 11(02): 139-144
DOI: 10.1055/s-0044-1787665
Case Report

Corticomedullary Differentiation in Fetal Kidneys: A Necessary Evil?

Ashutosh Gupta
1   Department of Foetal Medicine and Medical Genetics, Artemis Hospitals, Gurgaon, Haryana, India
,
Anjila Aneja
2   Department of Minimal Access Surgery (Gynaecology), Fortis Memorial Research Institute, Gurgaon, Haryana, India
,
Neena Bahl
2   Department of Minimal Access Surgery (Gynaecology), Fortis Memorial Research Institute, Gurgaon, Haryana, India
,
Rupam Arora
3   Department of Obstetrics and Gynecology, Max Balaji Hospital, Cloudnine Hospital, New Delhi, India
,
Loveleena Nadir
4   Department of Obstetrics and Gynecology, Artemis Health Institute, Fortis La Femme, New Delhi, India
,
Pankaj Saini
5   Department of Radiology, Manipal Hospitals, Dwarka, Delhi, India
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Abstract

Renal corticomedullary differentiation (CMD) is a crucial indicator of fetal renal health and is detectable as early as 15 to 16 weeks of gestation. Abnormalities in CMD, such as accentuation or loss, may signal underlying renal diseases. CMD assessment via prenatal ultrasound evolves dynamically throughout gestation, reflecting changes in cortical echogenicity and cystic structures. While CMD alterations can indicate conditions like glomerulonephritis or obstructive uropathies, they also offer prognostic insights into future renal function. This case report highlights the importance of early detection and comprehensive evaluation of CMD for optimising prenatal renal care.

Keywords

corticomedullary differentiation - fetal kidneys - GFR - loss - NCCT - (PET)-SPECT - indicator - prenatal diagnosis


Publication History

Article published online:
22 July 2024

© 2024. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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