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CC BY 4.0 · World J Nucl Med 2024; 23(04): 292-294
DOI: 10.1055/s-0044-1788073
Case Report

Incidental Visualization of Gallbladder on Post-therapy [177Lu]Lu-DOTATATE Scintigraphy Mimicking a Liver Metastasis in a Duodenal Neuroendocrine Tumor

Parth Baberwal
1   Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, Maharashtra, India
,
Rahul Parghane
1   Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, Maharashtra, India
,
Sandip Basu 
1   Radiation Medicine Centre, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, Maharashtra, India
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Abstract

We present a rare case of physiological uptake of [177Lu]Lu-DOTATATE in the gallbladder, observed post-therapy, in a 47-year-old man with grade I duodenal neuroendocrine tumor (NET), despite no uptake being observed pre-therapy in the somatostatin receptor-positron emission tomography. On planar scintigraphy, the gallbladder uptake could have been misidentified as liver metastasis. By utilizing single photon emission computed tomography/computed tomography imaging, we were able to precisely localize the tracer and obtain anatomical morphological characteristics, thereby averting the potential for misinterpretation of liver metastasis resulting from the gallbladder's physiological uptake of [177Lu]Lu-DOTATATE in NET patients.

Keywords

neuroendocrine tumor (NET) - 68Ga-DOTATATE; [177Lu]Lu-DOTATATE - PET-CT - SPECT-CT - somatostatin receptor (SSTR) - peptide receptor radionuclide therapy (PRRT)


Publication History

Article published online:
04 July 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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