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DOI: 10.1055/s-0044-1788074
Demonstration of Resolution of Community-Acquired Pneumonia Over a Short Course of Antibiotics on [18F]FDG-PET/CT Undertaken for Suspected Perimyocarditis Evaluation
Abstract
A 28-year-old male presenting with left-sided pleuritic chest pain, cough, palpitation, and fever with mild ST depression in II, III, and aVF, raised troponin I, troponin T, creatine phosphokinase-MB, and erythrocyte sedimentation rate was referred for F-18 2-fluoro 2-deoxyglucose positron emission tomography with noncontrast computed tomography ([18F]FDG-PET/CT) to rule out perimyocarditis. The first scan revealed incidental finding of [18F]FDG avid left lobar pneumonia and inadequate myocardial suppression, thus perimyocarditis could not be ruled out. The clinician was informed and after counseling, patient consented for a repeat study post-high fat-low carbohydrate diet. A regional [18F]FDG-PET/CT on the 5th day revealed adequate myocardial suppression, ruling out perimyocarditis. However, the metabolic and anatomical resolution of previously noted left lobar pneumonia was also observed in such a span of time with the administered antibiotics.
Keywords
community-acquired pneumonia - [18F]FDG-PET/CT - antibiotics - perimyocarditis - early treatment responsePublikationsverlauf
Artikel online veröffentlicht:
04. Juli 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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References
- 1 Mackenzie G. The definition and classification of pneumonia. Pneumonia 2016; 8: 14
- 2 Hashefi M, Curiel R. Future and upcoming non-neoplastic applications of PET/CT imaging. Ann N Y Acad Sci 2011; 1228: 167-174
- 3 Torres A, Cilloniz C, Niederman MS. et al. Pneumonia. Nat Rev Dis Primers 2021; 7 (01) 25
- 4 Pahal P, Rajasurya V, Sharma S. Typical Bacterial Pneumonia. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing; 2024
- 5 Li Y, Behr S. Acute findings on FDG PET/CT: key imaging features and how to differentiate them from malignancy. Curr Radiol Rep 2020; 8 (11) 22
- 6 Kashefi A, Kuo J, Shelton DK. Molecular imaging in pulmonary diseases. AJR Am J Roentgenol 2011; 197 (02) 295-307
- 7 Becker W, Meller J. The role of nuclear medicine in infection and inflammation. Lancet Infect Dis 2001; 1 (05) 326-333
- 8 Langah R, Spicer K, Gebregziabher M, Gordon L. Effectiveness of prolonged fasting 18f-FDG PET-CT in the detection of cardiac sarcoidosis. J Nucl Cardiol 2009; 16 (05) 801-810
- 9 Masuda A, Naya M, Manabe O. et al. Administration of unfractionated heparin with prolonged fasting could reduce physiological 18F-fluorodeoxyglucose uptake in the heart. Acta Radiol 2016; 57 (06) 661-668
- 10 Neely JR, Morgan HE. Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. Annu Rev Physiol 1974; 36: 413-459
- 11 Romijn JA, Godfried MH, Hommes MJ, Endert E, Sauerwein HP. Decreased glucose oxidation during short-term starvation. Metabolism 1990; 39 (05) 525-530
- 12 Ito K, Morooka M, Okazaki O, Minaminoto R, Kubota K, Hiroe M. Efficacy of heparin loading during an 18F-FDG PET/CT examination to search for cardiac sarcoidosis activity. Clin Nucl Med 2013; 38 (02) 128-130