Download PDF
CC BY 4.0 · Journal of Digestive Endoscopy 2024; 15(03): 197-202
DOI: 10.1055/s-0044-1788707
Case Report

Endoscopic Evaluation and Management of Superficial Esophageal Squamous Cell Carcinoma

Priscilla Lopez 
1   Department of Surgery Clinica Las Condes, Santiago, Chile
2   Department of Therapeutic endoscopy Instituto Chileno- Japonés de enfermedades digestivas, Santiago, Chile
,
Mohan Ramchandani
3   Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India
,
Sundeep Lakhtakia
3   Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India
,
Anuradha Sekaran
3   Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India
,
Pradev Inavolu
3   Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India
,
Nageshwar Reddy
3   Department of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India
› Author Affiliations
› Further Information
Also available at
   Permissions and Reprints

Abstract

Esophageal squamous cell carcinoma (SCC) is the seventh most common malignancy and the sixth leading cause of cancer-related deaths globally, demanding precise diagnostic and individualized therapeutic interventions. This case study describes the diagnosis and treatment of esophageal SCC in a 54-year-old man initially detected during an upper gastrointestinal endoscopy. The lesion was identified using narrow-band imaging and magnifying endoscopy; after imaging studies, it was treated with endoscopic submucosal dissection (ESD). ESD is known for its minimal invasiveness and the definitive histopathological evaluation it facilitates.

The management strategy described in this paper reiterates the criticality of extensive pretreatment evaluations, the indication of the application of ESD, and the importance of a multidisciplinary team. It underscores the significance of careful posttreatment monitoring and the informed selection of adjuvant therapies, particularly in areas like India, where such advanced endoscopic techniques are still on the rise.

Keywords

early esophageal cancer - endoscopic submucosal dissection - esophageal cancer - esophageal squamous cell carcinoma - intrapapillary capillary loop


Publication History

Article published online:
16 September 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Sung H, Ferlay J, Siegel RL. et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021; 71 (03) 209-249
    CrossrefPubMedSearch in Google Scholar
  • 2 Kitagawa Y, Uno T, Oyama T. et al. Esophageal Cancer Practice Guidelines 2017 edited by the Japan Esophageal Society: part 2. Esophagus 2019; 16 (01) 25-43
    CrossrefPubMedSearch in Google Scholar
  • 3 Pimentel-Nunes P, Libânio D, Bastiaansen BAJ. et al. Endoscopic submucosal dissection for superficial gastrointestinal lesions: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - update 2022. Endoscopy 2022; 54 (06) 591-622
    Thieme ConnectPubMedSearch in Google Scholar
  • 4 Oyama T, Inoue H, Arima M. et al. Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology: magnifying endoscopic classification of the Japan Esophageal Society. Esophagus 2017; 14 (02) 105-112
    CrossrefPubMedSearch in Google Scholar
  • 5 Ishihara R, Arima M, Iizuka T. et al; Japan Gastroenterological Endoscopy Society Guidelines Committee of ESD/EMR for Esophageal Cancer. Endoscopic submucosal dissection/endoscopic mucosal resection guidelines for esophageal cancer. Dig Endosc 2020; 32 (04) 452-493
    CrossrefPubMedSearch in Google Scholar
  • 6 Inoue H, Kaga M, Ikeda H. et al. Magnification endoscopy in esophageal squamous cell carcinoma: a review of the intrapapillary capillary loop classification. Ann Gastroenterol 2015; 28 (01) 41-48
    PubMedSearch in Google Scholar
  • 7 Okubo Y, Ishihara R. Endoscopic submucosal dissection for esophageal cancer: current and future. Life (Basel) 2023; 13 (04) 13
    Search in Google Scholar
  • 8 Al-Haddad MA, Elhanafi SE, Forbes N. , et al; ( ASGE Standards of Practice Committee Chair. American Society for Gastrointestinal Endoscopy guideline on endoscopic submucosal dissection for the management of early esophageal and gastric cancers: methodology and review of evidence. Gastrointest Endosc 2023; 98 (03) 285-305.e38
    CrossrefPubMedSearch in Google Scholar
  • 9 Kim SJ, Kim GH, Lee MW. et al. New magnifying endoscopic classification for superficial esophageal squamous cell carcinoma. World J Gastroenterol 2017; 23 (24) 4416-4421
    CrossrefPubMedSearch in Google Scholar
  • 10 Tanaka I, Hirasawa D, Saito H. et al. The sub-classification of type B2 vessels according to the magnifying endoscopic classification of the Japan Esophageal Society. Dig Endosc 2020; 32 (01) 49-55
    CrossrefPubMedSearch in Google Scholar
  • 11 Ueda T, Dohi O, Naito Y. et al. Diagnostic performance of magnifying blue laser imaging versus magnifying narrow-band imaging for identifying the depth of invasion of superficial esophageal squamous cell carcinoma. Dis Esophagus 2021; 34 (03) 34
    CrossrefPubMedSearch in Google Scholar