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CC BY 4.0 · Arq Neuropsiquiatr 2024; 82(10): s00441789228
DOI: 10.1055/s-0044-1789228
Original Article

Big data analysis of endovascular treatment for acute ischemic stroke: a study based on bibliometric analysis

Análise de big data de tratamento endovascular de acidente vascular cerebral isquêmico agudo: um estudo baseado em análise bibliométrica

Authors

  • Xin Lu 

    1   Yanbian University Hospital, Department of Neurology, Yanji, Jilin Province, China.

  • Huiying Che 

    2   Yanbian University Hospital, Department of General Practice, Yanji, Jilin Province, China.

  • Hongjian Guan 

    1   Yanbian University Hospital, Department of Neurology, Yanji, Jilin Province, China.
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Abstract

Background While bibliometric analyses are prevalent in the medical field, few have focused on ther endovascular treatment for acute ischemic stroke (AIS).

Objective To employ big data analysis to examine the research status, trends, and hotspots in endovascular treatment for AIS.

Methods We conducted a comprehensive search using the Web of Science (WOS) database to identify relevant articles on the endovascular treatment for AIS from 1980 to the present. We used various tools for data analysis, including an online platform (https://bibliometric.com/app), the Citespace software, the Vosviewer software, and the ArcMap software, version 10.8. A number of bibliometric indicators were collected and analyzed, such as publication date, country where the studies were conducted, institutions to which the authors were affiliated, authors, high-frequency keywords, cooperative relationship etc.

Results A total of 5,576 articles were retrieved. A substantial increase in the number of articles occurred after 2010. High-frequency keywords included terms such as large vessel occlusion, reperfusion, outcome, and basilar artery occlusion. Among the top 10 most productive authors, Raul G. Nogueira ranked first, with 136 published articles. Among the journals, The New England Journal of Medicine ranked first, with 5,631 citations. The United States has the closest collaborative ties with other nations.

Conclusion In the present study, we found that the reports of endovascular treatment for AIS gradually increased after 2010. Among them, Raul G. Nogueira was the most productive author in this field. The New England Journal of Medicine was the most cited, and it had the greatest impact. The Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands (MR CLEAN) trial study was the most cited, and it was a landmark study. There are many interesting studies on endovascular treatment for AIS, such as ischemic penumbra, collateral circulation, bridging therapy etc.

Resumo

Antecedentes Embora as análises bibliométricas sejam predominantes na área médica, poucas se concentraram no tratamento endovascular para acidente vascular cerebral isquêmico (AVCI) agudo.

Objetivo Empregar análise de big data para examinar o status da pesquisa, tendências e pontos críticos no tratamento endovascular para AVCI.

Métodos Realizamos uma pesquisa abrangente usando o banco de dados Web of Science (WOS) para identificar artigos relevantes sobre o tratamento endovascular para AVCI de 1980 até o presente. Usamos várias ferramentas para análise de dados, incluindo uma plataforma on-line (https://bibliometric.com/app), os softwares Citespace, Vosviewer e ArcMap, versão 10.8. Vários indicadores bibliométricos foram coletados e analisados, como data de publicação, país onde os estudos foram conduzidos, instituições às quais os autores eram afiliados, autores, palavras-chave de alta frequência, relacionamento cooperativo etc.

Resultados Um total de 5.576 artigos foram coletados. Um aumento substancial no número de artigos ocorreu após 2010. Palavras-chave de alta frequência incluíram termos como oclusão de grandes vasos, reperfusão, desfecho e oclusão da artéria basilar. Entre os dez autores mais produtivos, Raul G. Nogueira ficou em primeiro lugar, com 136 artigos publicados. Entre os periódicos, The New England Journal of Medicine ficou em primeiro lugar, com 5.631 citações. Os Estados Unidos têm os laços de colaboração mais próximos com outras nações.

Conclusão No presente estudo, descobrimos que os relatos de tratamento endovascular para AVCI aumentaram gradualmente após 2010. Entre eles, Raul G. Nogueira foi o autor mais produtivo neste campo. A revista The New England Journal of Medicine foi a mais citada e teve o maior impacto. O estudo clínico Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands (MR CLEAN) foi o mais citado e foi um estudo de destaque. Existem muitos estudos interessantes sobre tratamento endovascular para AVCI, como penumbra isquêmica, circulação colateral, terapia de ponte etc.

Keywords

Ischemic Stroke - Bibliometrics - Big Data

Palavras-chave

AVC Isquêmico - Bibliometria - Big Data

Authors' Contributions

XL: investigation, software, writing – original draft; HC: supervision, validation, visualization; HG: conceptualization, project administration, methodology, writing – review & editing. XL and HC contributed to the work equally, and should be regarded as co-first authors.




Publication History

Received: 05 January 2024

Accepted: 27 May 2024

Article published online:
31 August 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Xin Lu, Huiying Che, Hongjian Guan. Big data analysis of endovascular treatment for acute ischemic stroke: a study based on bibliometric analysis. Arq Neuropsiquiatr 2024; 82: s00441789228.
DOI: 10.1055/s-0044-1789228
 

  • References

  • 1 Saver JL, Goyal M, Bonafe A. et al; SWIFT PRIME Investigators. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015; 372 (24) 2285-2295
    CrossrefPubMedSearch in Google Scholar
  • 2 Broderick JP, Palesch YY, Demchuk AM. et al; Interventional Management of Stroke (IMS) III Investigators. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 2013; 368 (10) 893-903
    CrossrefPubMedSearch in Google Scholar
  • 3 Jovin TG, Chamorro A, Cobo E. et al; REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015; 372 (24) 2296-2306
    CrossrefPubMedSearch in Google Scholar
  • 4 Goyal M, Demchuk AM, Menon BK. et al; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015; 372 (11) 1019-1030
    CrossrefPubMedSearch in Google Scholar
  • 5 Campbell BC, Mitchell PJ, Kleinig TJ. et al; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015; 372 (11) 1009-1018
    CrossrefPubMedSearch in Google Scholar
  • 6 Berkhemer OA, Fransen PS, Beumer D. et al; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015; 372 (01) 11-20
    CrossrefPubMedSearch in Google Scholar
  • 7 Dávalos A, Cobo E, Molina CA. et al; REVASCAT Trial Investigators. Safety and efficacy of thrombectomy in acute ischaemic stroke (REVASCAT): 1-year follow-up of a randomised open-label trial. Lancet Neurol 2017; 16 (05) 369-376
    CrossrefPubMedSearch in Google Scholar
  • 8 Goyal M, Menon BK, van Zwam WH. et al; HERMES collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016; 387 (10029): 1723-1731
    CrossrefPubMedSearch in Google Scholar
  • 9 Albers GW, Lansberg MG, Kemp S. et al. A multicenter randomized controlled trial of endovascular therapy following imaging evaluation for ischemic stroke (DEFUSE 3). Int J Stroke 2017; 12 (08) 896-905
    CrossrefPubMedSearch in Google Scholar
  • 10 Ben Hassen W, Malley C, Boulouis G. et al. Inter- and intraobserver reliability for angiographic leptomeningeal collateral flow assessment by the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR) scale. J Neurointerv Surg 2019; 11 (04) 338-341
    CrossrefPubMedSearch in Google Scholar
  • 11 Thomalla G, Simonsen CZ, Boutitie F. et al; WAKE-UP Investigators. MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. N Engl J Med 2018; 379 (07) 611-622
    CrossrefPubMedSearch in Google Scholar
  • 12 Albers GW, Marks MP, Kemp S. et al; DEFUSE 3 Investigators. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med 2018; 378 (08) 708-718
    Search in Google Scholar
  • 13 Nogueira RG, Jadhav AP, Haussen DC. et al; DAWN Trial Investigators. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med 2018; 378 (01) 11-21
    Search in Google Scholar
  • 14 Zhang J, Wang Y, Ju Y, Jiang H. Endovascular treatment of acute basilar artery occlusion: A systematic review and meta-analysis of first-line stent retriever versus direct aspiration. Brain Behav 2023; 13 (08) e3141
    CrossrefPubMedSearch in Google Scholar
  • 15 Turk III AS, Siddiqui A, Fifi JT. et al. Aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion (COMPASS): a multicentre, randomised, open label, blinded outcome, non-inferiority trial. Lancet 2019; 393 (10175): 998-1008
    CrossrefPubMedSearch in Google Scholar
  • 16 Yang P, Treurniet KM, Zhang L. et al; DIRECT-MT investigators. Direct Intra-arterial thrombectomy in order to Revascularize AIS patients with large vessel occlusion Efficiently in Chinese Tertiary hospitals: A Multicenter randomized clinical Trial (DIRECT-MT)-Protocol. Int J Stroke 2020; 15 (06) 689-698
    CrossrefPubMedSearch in Google Scholar
  • 17 Zi W, Qiu Z, Li F. et al; DEVT Trial Investigators. Effect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial. JAMA 2021; 325 (03) 234-243
    CrossrefPubMedSearch in Google Scholar
  • 18 Suzuki K, Matsumaru Y, Takeuchi M. et al; SKIP Study Investigators. Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial. JAMA 2021; 325 (03) 244-253
    CrossrefPubMedSearch in Google Scholar
  • 19 van den Berg SA, Uniken Venema SM, LeCouffe NE. et al. Admission blood pressure and clinical outcomes in patients with acute ischaemic stroke treated with intravenous alteplase and endovascular treatment versus endovascular treatment alone: A MR CLEAN-NO IV substudy. Eur Stroke J 2023; 8 (03) 647-654
    CrossrefPubMedSearch in Google Scholar
  • 20 Fischer U, Kaesmacher J. , S Plattner P, et al; SWIFT DIRECT study investigators. SWIFT DIRECT: Solitaire™ With the Intention For Thrombectomy Plus Intravenous t-PA Versus DIRECT Solitaire™ Stent-retriever Thrombectomy in Acute Anterior Circulation Stroke: Methodology of a randomized, controlled, multicentre study. Int J Stroke 2022; 17 (06) 698-705
    CrossrefPubMedSearch in Google Scholar
  • 21 Mitchell PJ, Yan B, Churilov L. et al; DIRECT-SAFE Investigators. DIRECT-SAFE: A Randomized Controlled Trial of DIRECT Endovascular Clot Retrieval versus Standard Bridging Therapy. J Stroke 2022; 24 (01) 57-64
    CrossrefPubMedSearch in Google Scholar
  • 22 Mistry EA, Mistry AM, Nakawah MO. et al. Mechanical Thrombectomy Outcomes With and Without Intravenous Thrombolysis in Stroke Patients: A Meta-Analysis. Stroke 2017; 48 (09) 2450-2456
    CrossrefPubMedSearch in Google Scholar
  • 23 Powers WJ, Rabinstein AA, Ackerson T. et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 2019; 50 (12) e344-e418
    Search in Google Scholar
  • 24 Miyamoto S, Ogasawara K, Kuroda S. et al; Committee for Stroke Guideline 2021, the Japan Stroke Society. Japan Stroke Society Guideline 2021 for the Treatment of Stroke. Int J Stroke 2022; 17 (09) 1039-1049
    CrossrefPubMedSearch in Google Scholar
  • 25 Liu L, Li Z, Zhou H. et al. Chinese Stroke Association guidelines for clinical management of ischaemic cerebrovascular diseases: executive summary and 2023 update. Stroke Vasc Neurol 2023; 8 (06) e3
    CrossrefPubMedSearch in Google Scholar
  • 26 Huo X, Gao F, Sun X. et al. Endovascular Mechanical Thrombectomy with the Solitaire Device for the Treatment of Acute Basilar Artery Occlusion. World Neurosurg 2016; 89: 301-308
    CrossrefPubMedSearch in Google Scholar
  • 27 Fahed R, Di Maria F, Rosso C. et al. A leap forward in the endovascular management of acute basilar artery occlusion since the appearance of stent retrievers: a single-center comparative study. J Neurosurg 2017; 126 (05) 1578-1584
    CrossrefPubMedSearch in Google Scholar
  • 28 Liu X, Dai Q, Ye R. et al; BEST Trial Investigators. Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial. Lancet Neurol 2020; 19 (02) 115-122
    CrossrefPubMedSearch in Google Scholar
  • 29 Langezaal LCM, van der Hoeven EJRJ, Mont'Alverne FJA. et al; BASICS Study Group. Endovascular Therapy for Stroke Due to Basilar-Artery Occlusion. N Engl J Med 2021; 384 (20) 1910-1920
    CrossrefPubMedSearch in Google Scholar
  • 30 Tao C, Nogueira RG, Zhu Y. et al; ATTENTION Investigators. Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion. N Engl J Med 2022; 387 (15) 1361-1372
    CrossrefPubMedSearch in Google Scholar
  • 31 Jovin TG, Li C, Wu L. et al; BAOCHE Investigators. Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion. N Engl J Med 2022; 387 (15) 1373-1384
    CrossrefPubMedSearch in Google Scholar
  • 32 Li Z, Ma H, Li B. et al; DIRECT-MT Investigators. Impact of anesthesia modalities on functional outcome of mechanical thrombectomy in patients with acute ischemic stroke: a subgroup analysis of DIRECT-MT trial. Eur J Med Res 2023; 28 (01) 228
    CrossrefPubMedSearch in Google Scholar
  • 33 Sarraj A, Albers GW, Mitchell PJ. et al; SELECT, EXTEND-IA, EXTEND-IA TNK, and EXTEND-IA TNK Part-II Investigators. Thrombectomy Outcomes With General vs Nongeneral Anesthesia: A Pooled Patient-Level Analysis From the EXTEND-IA Trials and SELECT Study. Neurology 2023; 100 (03) e336-e347
    CrossrefPubMedSearch in Google Scholar
  • 34 Hoefnagel AL, Yao J, Rao D, Kovacs P, Brzezicki G, Mongan PD. Anesthesia, Blood Pressure, and Socioeconomic Status in Endovascular Thrombectomy for Acute Stroke: A Single Center Retrospective Case Cohort. J Neurosurg Anesthesiol 2023; 35 (01) 41-48
    CrossrefPubMedSearch in Google Scholar
  • 35 Vinay B, Manohara N, Lobo FA, Lee-St John T, Lamperti M. Inhalational versus Intravenous General Anesthesia for mechanical thrombectomy for stroke: A single centre retrospective study. Clin Neurol Neurosurg 2023; 229: 107719
    CrossrefPubMedSearch in Google Scholar
  • 36 Lally F, Grunwald IQ, Sanyal R, Natarajan I, Roffe C. Mechanical thrombectomy in acute ischaemic stroke: a review of the literature, clinical effectiveness and future use. CNS Neurol Disord Drug Targets 2013; 12 (02) 170-190
    CrossrefPubMedSearch in Google Scholar
  • 37 Son S, Choi DS, Oh MK. et al. Comparison of Solitaire thrombectomy and Penumbra suction thrombectomy in patients with acute ischemic stroke caused by basilar artery occlusion. J Neurointerv Surg 2016; 8 (01) 13-18
    CrossrefPubMedSearch in Google Scholar
  • 38 Asif KS, Otite FO, Desai SM. et al; Global Executive Committee of the MT-GLASS Study. Mechanical Thrombectomy Global Access For Stroke (MT-GLASS): A Mission Thrombectomy (MT-2020 Plus) Study. Circulation 2023; 147 (16) 1208-1220
    CrossrefPubMedSearch in Google Scholar
  • 39 Lin CH, Liebeskind DS, Ovbiagele B, Lee M, Saver JL. Efficacy of endovascular therapy for basilar and vertebral artery occlusion: A systematic review and meta-analysis of randomized controlled trials. Eur J Intern Med 2023; 110: 22-28
    CrossrefPubMedSearch in Google Scholar
  • 40 Abdalkader M, Finitsis S, Li C. et al; BasilaR Artery Ischemia Network STudy of Endovascular versus Medical Management (BRAINSTEM) Group. Endovascular versus Medical Management of Acute Basilar Artery Occlusion: A Systematic Review and Meta-Analysis of the Randomized Controlled Trials. J Stroke 2023; 25 (01) 81-91
    CrossrefPubMedSearch in Google Scholar
  • 41 Alemseged F, Nguyen TN, Alverne FM, Liu X, Schonewille WJ, Nogueira RG. Endovascular Therapy for Basilar Artery Occlusion. Stroke 2023; 54 (04) 1127-1137
    CrossrefPubMedSearch in Google Scholar
  • 42 Siegler JE, Qureshi MM, Nogueira RG. et al. Endovascular vs Medical Management for Late Anterior Large Vessel Occlusion With Prestroke Disability: Analysis of CLEAR and RESCUE-Japan. Neurology 2023; 100 (07) e751-e763
    CrossrefPubMedSearch in Google Scholar
  • 43 Goyal M, Singh N, Ospel J. Clinical trials in stroke in 2022: new answers and questions. Lancet Neurol 2023; 22 (01) 9-10
    CrossrefPubMedSearch in Google Scholar
  • 44 Ospel JM, Kunz WG, McDonough RV. et al; HERMES Investigators. Cost-Effectiveness of Endovascular Treatment in Large Vessel Occlusion Stroke With Mild Prestroke Disability: Results From the HERMES Collaboration. Stroke 2023; 54 (01) 226-233
    CrossrefPubMedSearch in Google Scholar
  • 45 Powers WJ, Derdeyn CP, Biller J, Coffey CS, Hoh BL, Jauch EC, Johnston KC, Johnston SC, Khalessi AA, Kidwell CS, Meschia JF, Ovbiagele B, Yavagal DR. American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment: A guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke; a Journal of Cerebral Circulation 2015; 46 (10) 3020-3035
    CrossrefPubMedSearch in Google Scholar
  • 46 Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CB, Dippel DW, Campbell BC, Nogueira RG, Demchuk AM, Tomasello A, Cardona P, Devlin TG, Frei DF, du Mesnil de Rochemont R, Berkhemer OA, Jovin TG, Siddiqui AH, van Zwam WH, Davis SM, Castaño C, Sapkota BL, Fransen PS, Molina C, van Oostenbrugge RJ, Chamorro Á, Lingsma H, Silver FL, Donnan GA, Shuaib A, Brown S, Stouch B, Mitchell PJ, Davalos A, Roos YB, Hill MD. HERMES Collaborators. Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. JAMA 2016; 27 (12) 1279-88
    CrossrefPubMedSearch in Google Scholar
  • 47 Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, Feng L, Meyer BC, Olson S, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Guzy J, Starkman S, Saver JL. MR RESCUE Investigators. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 2013; 368 (10) 914-23
    CrossrefPubMedSearch in Google Scholar
  • 48 Saver JL, Jahan R, Levy EI, Jovin TG, Baxter B, Nogueira RG, Clark W, Budzik R, Zaidat OO. SWIFT Trialists. Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet 2012; 380 (9849) 1241-9
    CrossrefPubMedSearch in Google Scholar
  • 49 Singh P, Kaur R, Kaur A. Endovascular treatment of acute ischemic stroke. J Neurosci Rural Pract 2013; 4 (03) 298-303
    Thieme ConnectPubMedSearch in Google Scholar