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DOI: 10.1055/s-0044-1790567
Clinicopathological Analysis and Survival of Patients with Cervical Cancer Submitted to Pelvic Exenteration
Funding The authors declare that they did not receive funding from agencies in the public, private or non-profit sectors to conduct the present study.Clinical Trials? No
Abstract
Justification The importance of this study arises from the high incidence and mortality of cervical cancer (CC), and the need to evaluate the effectiveness of current treatments, such as pelvic exenteration, performed in cases of persistent or recurrent carcinoma.
Objective To analyze the relationship between clinical and pathological factors and the results of mortality and recurrence in patients with CC who underwent pelvic exenteration at the Hospital Haroldo Juaçaba, from 2000 to 2019, aiming to improve the understanding of this procedure's outcomes.
Materials and Methods Observational, cross-sectional, retrospective study, using medical record consultation.
Results Patients with perineural invasion, those with prior surgical treatment, and those who underwent radical surgery had lower disease-free survival rates. Also, patients over 50-years-old had lower overall survival than those under that age range.
Conclusion Pelvic exenteration is a high-risk treatment for malignant pelvic neoplasms, with results influenced by technique and institutional resources. Despite the risks, it can control the disease in the long term and even cure it. However, it can affect quality of life and sexual function. Young patients should be made aware of CC prevention methods.
Author's Contribution
BMPA: data collection, assembly, analysis, and interpretation, study conception and design, writing and final approval of the manuscript, provision of study materials or patients. FLM: data analysis and interpretation, final approval of the manuscript. HFCN: writing and final approval of the manuscript, provision of study materials or patient. BSS: collection and assembly of data, final approval of the manuscript. JSO: collection and assembly of data, study conception and design.
Publikationsverlauf
Eingereicht: 05. Mai 2024
Angenommen: 18. Juli 2024
Artikel online veröffentlicht:
28. September 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
Bruno Marinho Pinto Águila, Felipe de Lima Monteiro, Héladio Feitosa de Castro Neto, Bruno de Sousa Soares, Jefferson Silva Oliveira, Rodrigo de Oliveira Lima. Clinicopathological Analysis and Survival of Patients with Cervical Cancer Submitted to Pelvic Exenteration. Brazilian Journal of Oncology 2024; 20: s00441790567.
DOI: 10.1055/s-0044-1790567
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