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DOI: 10.1055/s-0044-1800918
Acquiring a Comprehensive Awareness of the Current Insights on Pediatric Oral and Maxillofacial Malignancies

Abstract
Orofacial tumors constitute a heterogeneous collection of pathological conditions characterized by distinct types of histology and clinical behaviors. Numerous accounts of craniofacial tumors in kids and young adults are being recorded globally. Within the pediatric population, leukemia, lymphoma, and nervous system tumors are the most common forms of pediatric cancer in developing nations; yet, when concentrating on specific anatomical regions, such as the head and neck, the incidence of malignant tumors is comparatively low. Additionally, the occurrence of oral and maxillofacial malignancy in pediatric populations is rare, varying from roughly 0.5 to 6%. The authors of this article conducted a comprehensive retrospective review of various cases and studies concerning oral and maxillofacial malignancies in the pediatric population, utilizing electronic databases, such as PubMed, Scopus, Web of Science, and Google Scholar to identify pertinent articles. We performed a narrative review on the current aspects and therapeutic procedures related to the four most prevalent oral and maxillofacial malignancies: Burkitt's lymphoma, mucoepidermoid carcinoma, rhabdomyosarcoma, and osteosarcoma.
Publication History
Article published online:
05 February 2025
© 2025. European Dental Research and Biomaterials Journal. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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