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CC BY 4.0 · Indian Journal of Neurosurgery
DOI: 10.1055/s-0045-1804882
Brief Report

Depressed Skull Fracture and Cerebrospinal Fluid Rhinorrhea: A Rare Complication after Gamma Knife Radiosurgery Frame Fixation

Subhashree Hari
1   Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Research Center, Mumbai, Maharashtra, India
,
Alay Khandhar 
1   Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Research Center, Mumbai, Maharashtra, India
,
Ketan Desai
1   Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Research Center, Mumbai, Maharashtra, India
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Abstract

Gamma Knife radiosurgery (GKRS) is a widely used minimally invasive alternative procedure to the traditional microsurgery with negligible major procedure-related complications. The common complications include postprocedure headaches, nausea, and, in rare instances, radiation-induced edema leading to seizures and neurological deficits. We present our experience with a 75-year-old gentleman who experienced an unseen complication of a depressed frontal bone fracture and cerebrospinal fluid leakage during the stereotactic frame fixation for GKRS. Anatomical variations like enlarged frontal sinus, postcraniotomy bony defects, osteoporotic bones, systemic causes like metastatic tumors, hyperparathyroidism, granulomatous diseases, and bony anomalies leading to frontal cortex thinning must be kept in mind during the frame fixation for GKRS.

Keywords

Gamma Knife radiosurgery - depressed skull fracture - cerebrospinal fluid rhinorrhea

Authors' Contribution

S.H. and A.K. contributed to the concept, design, definition of intellectual content, literature search, clinical studies, data acquisition, manuscript preparation, manuscript editing, and manuscript review. K.D. contributed to the concept, design, definition of intellectual content, literature search, clinical studies, manuscript editing, and manuscript review.




Publikationsverlauf

Artikel online veröffentlicht:
02. April 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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