Subscribe to RSS
DOI: 10.1055/s-0045-1804899
Differential Diagnosis for Intestinal Tuberculosis in Elder Patient – Case Report
Abstract
Introduction Intestinal tuberculosis (ITB) presents with clinical features that often mimic malignant or inflammatory diseases. Diagnosis is established through a combination of endoscopic, radiological, and pathological findings.
Case A 76-year-old woman presented with acute, diffuse abdominal pain. Computed tomography (CT) of the abdomen revealed subocclusion due to wall thickening at the ileocecal transition. A colonoscopy biopsy showed ulcerated granulomatous lesions, with negative results for AFB. Enterography suggested the possibility of a neoplastic disease. Due to the subocclusion, the patient underwent a segmental right ileocolectomy and ileocolostomy with a double-barrel stoma. Histopathological analysis of the resected specimen, including frozen section examination, confirmed ITB.
Conclusion The diagnosis of ITB is challenging due to its clinical, endoscopic, radiologic, and histopathologic features, which overlap with neoplasms and inflammatory bowel disease. Therefore, establishing an appropriate therapeutic approach requires the integration of multiple diagnostic findings.
Authors' Contribution
Thaís Tuasca Jareño: conceptualization, investigation, formal analysis, data curation, writing – original draft, writing – review & editing; Bruno Salgueiro Russo: investigation, formal analysis, data curation, writing – review & editing; visualization; Lucas Moreto Betini: conceptualization, investigation, formal analysis, data curation, project administration, writing – original draft, writing – review & editing; Isadora Pêsso: resources; writing – review & editing; Vitória Giordano: data curation, writing – review & editing; Fang Chia Bin: conceptualization, investigation, formal analysis, data curation, project administration, supervision, writing – original draft, writing – review & editing.
Publication History
Received: 08 May 2024
Accepted: 24 July 2024
Article published online:
17 April 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua Rego Freitas, 175, loja 1, República, São Paulo, SP, CEP 01220-010, Brazil
Thaís Tuasca Jareño, Bruno Salgueiro Russo, Lucas Moreto Betini, Isadora Pêsso, Vitória Giordano, Fang Chia Bin. Differential Diagnosis for Intestinal Tuberculosis in Elder Patient – Case Report. Journal of Coloproctology 2025; 45: s00451804899.
DOI: 10.1055/s-0045-1804899
-
References
- 1 dos Santos GM, Carrijo AMM, Paulinelli AJC, Queiroz Gde A, e Silva LdeLC, de Oliveira SV. Hospitalizações por tuberculose na Região Sudeste: uma análise epidemiológica. Rev Med (São Paulo) 2023;102(02): Available from https://www.revistas.usp.br/revistadc/article/download/197288/192660/616125 cited 2023 Oct 9 [Internet]
- 2 Boletim Epidemiológico de Tuberculose – Número Especial |Mar.2023 -Ministério da Saúde [Internet]. www.gov.br. Available from: https://www.gov.br/saude/pt-br/centrais-de-conteudo/pub-licacoes/boletins/epidemiologicos/especiais/2023/boletim-epide-miologico-de-tuberculose-numero-especial-mar.2023/view
- 3 Suárez-Noya A, González-Bernardo O, Riera-Velasco JR, Suárez A. Intestinal tuberculosis mimicking colon cancer. Rev Gastroenterol Mex (Engl Ed) 2023; 88 (02) 183-186
- 4 Merino Gallego E, Gallardo Sánchez F, Gallego Rojo FJ. Intestinal tuberculosis and Crohn's disease: the importance and difficulty of a differential diagnosis. Rev Esp Enferm Dig 2018; 110 (10) 650-657
- 5 Weinberg SE, Mughal AM. A Case of Intestinal Tuberculosis Mimicking Crohn's Disease: A Clinical and Diagnostic Dilemma. Eur J Case Rep Intern Med 2021; 8 (11) 002699 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668007/ cited 2022Mar10 [Internet]
- 6 Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin 2020; 70 (01) 7-30
- 7 Seth R, Gupta P, Debi U, Prasad KK, Singh H, Sharma V. Perfusion Computed Tomography May Help in Discriminating Gastrointestinal Tuberculosis and Crohn's Disease. Diagnostics (Basel) 2023; 13 (07) 1255-5
- 8 Ocasio Quinones GA, Khan Suheb MZ, Woolf A. Small Bowel Cancer [Internet]. PubMed. Treasure Island (FL): StatPearls Pub-lishing; 2022. . Available from: https://www.ncbi.nlm.nih.gov/books/NBK560725/
- 9 Bilimoria KY, Bentrem DJ, Wayne JD, Ko CY, Bennett CL, Talamonti MS. Small bowel cancer in the United States: changes in epidemi-ology, treatment, and survival over the last 20 years. Ann Surg 2009; 249 (01) 63-71
- 10 Cahill C, Gordon PH, Petrucci A, Boutros M. Small bowel adenocarcinoma and Crohn's disease: any further ahead than 50 years ago?. World J Gastroenterol 2014; 20 (33) 11486-11495
- 11 Annese V. Small Bowel Adenocarcinoma in Crohn's Disease: An Underestimated Risk?. J Crohns Colitis 2020; 14 (03) 285-286