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CC BY 4.0 · Ibnosina Journal of Medicine and Biomedical Sciences 2025; 17(01): 025-032
DOI: 10.1055/s-0045-1805027
Original Article

Physicians' Perceptions and Practices on Metabolic Dysfunction-Associated Liver Disease: An Exploratory Survey

Salem A. Beshyah 
1   Department of Medicine, New Medical Center Royal Hospital, Mohamed Bin Zayed City, Abu Dhabi, United Arab Emirates
2   Department of Medicine, Dubai Medical College for Girls, Dubai, United Arab Emirates
,
Khadijah A. Hafidh 
2   Department of Medicine, Dubai Medical College for Girls, Dubai, United Arab Emirates
3   Department of Endocrinology, Rashid Hospital, DHA, Dubai, United Arab Emirates
,
Wail A. Eldukali
4   Gastroenterology and Hepatology Unit, Benghazi Medical Center, Benghazi, Libya
,
Ahmed A.K. Hassoun
5   Department of Endocrinology, Fakeeh University Hospital, Dubai, United Arab Emirates
› Institutsangaben Funding and Sponsorship None.
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Abstract

Background

There has been a rapid increase in the incidence and prevalence of metabolic dysfunction-associated liver disease (MASLD) in the Middle East and Africa (MEA) regions.

Methods

We aimed to assess the knowledge and awareness of MASLD among MEA physicians and evaluate their current approach to diagnosing, managing, and referring to MASLD. We used an online survey through a validated questionnaire and a convenience sample of MEA clinicians to examine knowledge, practices, and attitudes regarding MASLD and the barriers to providing care for this condition.

Results

A total of 128 clinicians completed the survey. Most were from the Arabian Gulf and the Middle East (72.6%). Most were senior adult endocrinologists; 53.2% of respondents considered the prevalence of MASLD in the general population around 10% or 30%; 28.6% of respondents felt that liver enzymes were sufficiently sensitive to detect underlying MASLD. Most respondents were unsure whether the Enhanced Liver Fibrosis score or Fibrosis 4 score could help to identify those with high risk for advanced fibrosis or cirrhosis (54.5 and 29.1%, respectively, were unsure). Although 83.8% of respondents would refer a patient to a gastroenterologist if they suspect the patient has MASLD, 29.4% do not make referrals. Of concern, 64.5% of participants would unlikely refer a patient to a hepatologist unless liver function tests are abnormal. Respondents identified several barriers to making referrals.

Conclusion

Most respondents viewed MASLD as a significant health concern. However, the rates of screening for MASLD were low. A key obstacle in managing these patients was the lack of knowledge regarding MASLD. Regional guidelines and continuing professional development activities should focus on strategies for screening at-risk patients, and evidence-based management practices.

Keywords

metabolic dysfunction-associated liver disease (MASLD) - nonalcoholic steatohepatitis (NASH) - elastography - Enhanced Liver Fibrosis (ELF) - Fibrosis 4 (FIB 4) - Middle East and Africa - physicians perceptions

Availability of Data, had access to the data

The data sets used during the current study are available from the corresponding author upon reasonable request.


Authors' Contributions

S.A.B. was involved in data collection, analysis, writing, and research. All authors read and approved the final manuscript.


Compliance with Ethical Principles

The ethics review committee of the Sheikh Khalifa Medical City, Abu Dhabi, UAE, gave ethical approval. Participants gave electronic consent before they could proceed to the survey questionnaire.


Supplementary Material



Publikationsverlauf

Artikel online veröffentlicht:
28. Februar 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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