CC BY 4.0 · Arq Neuropsiquiatr 2025; 83(04): s00451806924
DOI: 10.1055/s-0045-1806924
Brazilian Academy of Neurology

A physiotherapy protocol* for stroke patients in acute hospital settings: expert consensus from the Brazilian early stroke rehabilitation task force

1   Hospital Geral Roberto Santos, Unidade de AVC, Salvador BA, Brazil.
2   Escola Bahiana de Medicina e Saúde Pública, Grupo de Pesquisa Comportamento Motor e Reabilitação Neurofuncional, Salvador BA, Brazil.
,
3   Universidade Federal do Triângulo Mineiro, Departamento de Fisioterapia Aplicada, Uberaba MG, Brazil.
,
3   Universidade Federal do Triângulo Mineiro, Departamento de Fisioterapia Aplicada, Uberaba MG, Brazil.
,
1   Hospital Geral Roberto Santos, Unidade de AVC, Salvador BA, Brazil.
2   Escola Bahiana de Medicina e Saúde Pública, Grupo de Pesquisa Comportamento Motor e Reabilitação Neurofuncional, Salvador BA, Brazil.
,
4   Universidade Estadual Paulista, Faculdade de Medicina de Botucatu, Botucatu SP, Brazil.
,
2   Escola Bahiana de Medicina e Saúde Pública, Grupo de Pesquisa Comportamento Motor e Reabilitação Neurofuncional, Salvador BA, Brazil.
,
5   Hospital Municipal São José, Programa de Residência Multiprofissional em Neurologia, Joinville SC, Brazil.
,
6   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Hospital das Clínicas, Unidade de AVC, Ribeirão Preto SP, Brazil.
,
7   Hospital São José, Unidade de AVC, Joinville SC, Brazil.
,
4   Universidade Estadual Paulista, Faculdade de Medicina de Botucatu, Botucatu SP, Brazil.
,
1   Hospital Geral Roberto Santos, Unidade de AVC, Salvador BA, Brazil.
8   Universidade Federal da Bahia, Instituto de Ciências da Saúde, Salvador BA, Brazil.
,
9   Santa Casa de São Paulo, Faculdade de Ciências Médicas, São Paulo SP, Brazil.
,
10   Hospital Carlos Fernando Malzoni, Matão SP, Brazil.
11   Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Programa de Pós-Graduação do Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.
,
12   Hospital de Clínicas de Porto Alegre, Porto Alegre RS, Brazil.
13   Universidade Federal do Rio Grande do Sul, Porto Alegre RS, Brazil.
14   Rede Brasil AVC, Porto Alegre RS, Brazil.
15   World Stroke Organization, Geneva, Switzerland.
,
16   Universidade Federal de Alagoas, Curso de Medicina, Arapiraca AL, Brazil.
› Author Affiliations

Abstract

The present protocol provides general recommendations based on the best evidence currently available for physiotherapists to use as a guide for the care of stroke patients during hospitalization. The Brazilian Early Stroke Rehabilitation Task Force, comprising physical therapy experts and researchers from different Brazilian states, was organized to develop this care protocol based on a bibliographical survey, including meta-analyses, systematic reviews, clinical trials, and other more recent and relevant scientific publications. Professionals working in stroke units were also included in the task force to ensure the practicality of the protocol in different contexts. This protocol provides guidance on assessment strategies, safety criteria for the mobilization of patients with stroke, recommendations for mobilization and proper positioning, as well as evidence-based practices for treatment during hospitalization, including preventive measures for shoulder pain and shoulder-hand syndrome. The protocol also provides information on the organization of the physiotherapy service at stroke units, guidelines for hospital discharge, and quality indicators for physiotherapy services. We have included detailed activities that can be performed during mobilization in the supplementary material, such as postural control training, sensory and perceptual stimulation, task-oriented training, and activities involving an enriched environment. The protocol was written in a user-friendly format to facilitate its application in different social and cultural contexts, utilizing resources readily available in most clinical settings.

Authors' Contributions

IM, GJL, JMAM, CFN, LAMB, EBP, FMK, RMS, PAPJ, JAOB: conceptualization, writing, review, editing, and validation of the original draft. CHCM, RB: conceptualization of the original draft and participation as reviewer. EMCR, CM, SOM: participation as reviewers. All authors reviewed and approved the final version of the manuscript.


Editor-in-Chief: Ayrton Roberto Massaro.


Associate Editor: Chien Hsin Fen.


*This protocol has been endorsed by the Brazilian Academy of Neurology and the Brazilian Association of Neurofunctional Physiotherapy.




Publication History

Received: 03 April 2024

Accepted: 03 February 2025

Article published online:
22 April 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

Thieme Revinter Publicações Ltda.
Rua Rego Freitas, 175, loja 1, República, São Paulo, SP, CEP 01220-010, Brazil

Bibliographical Record
Iara Maso, Gustavo José Luvizutto, Jéssica Mariana de Aquino Miranda, Carla Ferreira do Nascimento, Luana Aparecida Miranda Bonome, Elen Beatriz Pinto, Fabiane Maria Klitzke, Ricardo Machado Souza, Carla Heloisa Cabral Moro, Rodrigo Bazan, Pedro Antonio Pereira de Jesus, Eduardo de Melo Carvalho Rocha, Cesar Minelli, Sheila Ouriques Martins, Jussara Almeida de Oliveira Baggio. A physiotherapy protocol* for stroke patients in acute hospital settings: expert consensus from the Brazilian early stroke rehabilitation task force. Arq Neuropsiquiatr 2025; 83: s00451806924.
DOI: 10.1055/s-0045-1806924
 
  • References

  • 1 Vos T, Abajobir AA, Abate KH. et al; GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390 (10100): 1211-1259
  • 2 Ministério da Saúde. Departamento de Informática do Sistema Único de Saúde (DATASUS), http://www2.datasus.gov.br/DATASUS/index.php?area=0206&id=6942&VObj=http://tabnet.datasus.gov.br/cgi/deftohtm.exe?ibge/cnv/pop (2023, accessed 24 January 2023)
  • 3 Cieza A, Causey K, Kamenov K, Hanson SW, Chatterji S, Vos T. Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 2021; 396 (10267): 2006-2017
  • 4 Owolabi MO, Thrift AG, Martins S. et al; Stroke Experts Collaboration Group. The state of stroke services across the globe: Report of World Stroke Organization-World Health Organization surveys. Int J Stroke 2021; 16 (08) 889-901
  • 5 Martins SCO, Lavados P, Secchi TL. et al. Fighting Against Stroke in Latin America: A Joint Effort of Medical Professional Societies and Governments. Front Neurol 2021; 12 (October): 743732
  • 6 Bernhardt J, Hayward KS, Kwakkel G. et al. Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable taskforce. Int J Stroke 2017; 12 (05) 444-450
  • 7 Minelli C, Bazan R, Pedatella MTA. et al. Brazilian Academy of Neurology practice guidelines for stroke rehabilitation: part I. Arq Neuropsiquiatr 2022; 80 (06) 634-652
  • 8 Ouriques Martins SC, Sacks C, Hacke W. et al. Priorities to reduce the burden of stroke in Latin American countries. Lancet Neurol 2019; 18 (07) 674-683
  • 9 Rethnam V, Langhorne P, Churilov L. et al. Early mobilisation post-stroke: a systematic review and meta-analysis of individual participant data. Disabil Rehabil 2022; 44 (08) 1156-1163
  • 10 Winstein CJ, Stein J, Arena R. et al; American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Quality of Care and Outcomes Research. Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 2016; 47 (06) e98-e169
  • 11 Teasell R, Salbach NM, Foley N. et al. Canadian Stroke Best Practice Recommendations: Rehabilitation, Recovery, and Community Participation following Stroke. Part One: Rehabilitation and Recovery Following Stroke; 6th Edition Update 2019. Int J Stroke 2020; 15 (07) 763-788
  • 12 Stroke Foundation. Clinical Guidelines for Stroke Management, https://informme.org.au/guidelines/living-clinical-guidelines-for-stroke-management (2023, accessed 7 November 2023)
  • 13 Royal College of Physicians. National clinical guideline for stroke, https://www.rcplondon.ac.uk/guidelines-policy/stroke-guidelines-2016 (2016, accessed 7 November 2023)
  • 14 Li J, Zhang P, Wu S. et al. Stroke-related complications in large hemisphere infarction: incidence and influence on unfavorable outcome. Ther Adv Neurol Disord 2019; 12: 1756286419873264
  • 15 Phipps MS, Cronin CA. Management of acute ischemic stroke. BMJ 2020; 368: l6983
  • 16 Langhorne P, Ramachandra S. Stroke Unit Trialists' Collaboration. Organised inpatient (stroke unit) care for stroke: network meta-analysis. Cochrane Database Syst Rev 2020; 4 (04) CD000197
  • 17 Kwakkel G, Lannin NA, Borschmann K. et al. Standardized Measurement of Sensorimotor Recovery in Stroke Trials: Consensus-Based Core Recommendations from the Stroke Recovery and Rehabilitation Roundtable. Neurorehabil Neural Repair 2017; 31 (09) 784-792
  • 18 Academy of Neurologic Physical Therapy. StrokEDGE II Outcome Measures Acute Care, https://www.neuropt.org/docs/default-source/edge-updates-november-2021/stroke-edge-acute-care.pdf?sfvrsn=6f2f5c43_2 (2021, accessed 22 October 2024)
  • 19 Cincura C, Pontes-Neto OM, Neville IS. et al. Validation of the National Institutes of Health Stroke Scale, modified Rankin Scale and Barthel Index in Brazil: the role of cultural adaptation and structured interviewing. Cerebrovasc Dis 2009; 27 (02) 119-122
  • 20 Maso I, Pinto EB, Monteiro M. et al. A Simple Hospital Mobility Scale for Acute Ischemic Stroke Patients Predicts Long-term Functional Outcome. Neurorehabil Neural Repair 2019; 33 (08) 614-622
  • 21 Maso I, Mascarenhas L, Makhoul M. et al. Reliability and concurrent validity of the Hospital Mobility Scale in acute stroke patients. J Physiother Res 2020; 10 (03) 505-511
  • 22 Cheng DK, Nelson M, Brooks D, Salbach NM. Validation of stroke-specific protocols for the 10-meter walk test and 6-minute walk test conducted using 15-meter and 30-meter walkways. Top Stroke Rehabil 2020; 27 (04) 251-261
  • 23 Tilson JK, Sullivan KJ, Cen SY. et al; Locomotor Experience Applied Post Stroke (LEAPS) Investigative Team. Meaningful gait speed improvement during the first 60 days poststroke: minimal clinically important difference. Phys Ther 2010; 90 (02) 196-208
  • 24 Perera S, Mody SH, Woodman RC, Studenski SA. Meaningful change and responsiveness in common physical performance measures in older adults. J Am Geriatr Soc 2006; 54 (05) 743-749
  • 25 Borg GAV. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982; 14 (05) 377-381
  • 26 Wilson B, Cockburn J, Halligan P. Development of a behavioral test of visuospatial neglect. Arch Phys Med Rehabil 1987; 68 (02) 98-102
  • 27 Baggio JA, Santos-Pontelli TE, Cougo-Pinto PT. et al. Validation of a structured interview for telephone assessment of the modified Rankin Scale in Brazilian stroke patients. Cerebrovasc Dis 2014; 38 (04) 297-301
  • 28 Lin JH, Hsu MJ, Hsu HW, Wu HC, Hsieh CL. Psychometric comparisons of 3 functional ambulation measures for patients with stroke. Stroke 2010; 41 (09) 2021-2025
  • 29 Sullivan JE, Crowner BE, Kluding PM. et al. Outcome measures for individuals with stroke: process and recommendations from the American Physical Therapy Association neurology section task force. Phys Ther 2013; 93 (10) 1383-1396
  • 30 Ministério da Saúde - Brasil. Linha de cuidado do Acidente Vascular Cerebral (AVC) no adulto, https://linhasdecuidado.saude.gov.br/portal/acidente-vascular-cerebral-(AVC)-no-adulto/ (2020, accessed 25 October 2024)
  • 31 Duffy L, Gajree S, Langhorne P, Stott DJ, Quinn TJ. Reliability (inter-rater agreement) of the Barthel Index for assessment of stroke survivors: systematic review and meta-analysis. Stroke 2013; 44 (02) 462-468
  • 32 Barbas CSV, Ísola AM, Farias Ade C. et al. Brazilian recommendations of mechanical ventilation 2013. Part I. Rev Bras Ter Intensiva 2014; 26 (02) 89-121
  • 33 Barbas CSV, Ísola AM, Farias Ade C. et al. Brazilian recommendations of mechanical ventilation 2013. Part 2. Rev Bras Ter Intensiva 2014; 26 (03) 215-239
  • 34 Blakeman TC, Scott JB, Yoder MA, Capellari E, Strickland SL. AARC Clinical Practice Guidelines: Artificial Airway Suctioning. Respir Care 2022; 67 (02) 258-271
  • 35 Fan E, Del Sorbo L, Goligher EC. et al; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 2017; 195 (09) 1253-1263
  • 36 Keenan SP, Sinuff T, Burns KEA. et al; Canadian Critical Care Trials Group/Canadian Critical Care Society Noninvasive Ventilation Guidelines Group. Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting. CMAJ 2011; 183 (03) E195-E214
  • 37 MacIntyre NR, Cook DJ, Ely Jr EW. et al; American College of Chest Physicians, American Association for Respiratory Care, American College of Critical Care Medicine. Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. Chest 2001; 120 (6, Suppl) 375S-395S
  • 38 Mussa CC, Gomaa D, Rowley DD, Schmidt U, Ginier E, Strickland SL. AARC Clinical Practice Guideline: Management of Adult Patients with Tracheostomy in the Acute Care Setting. Respir Care 2021; 66 (01) 156-169
  • 39 Rochwerg B, Brochard L, Elliott MW. et al. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J 2017; 50 (02) 1602426
  • 40 Berbenetz N, Wang Y, Brown J. et al. Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema. Cochrane Database Syst Rev 2019; 4 (04) CD005351
  • 41 Robba C, Poole D, McNett M. et al. Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus. Intensive Care Med 2020; 46 (12) 2397-2410
  • 42 Young B, Moyer M, Pino W, Kung D, Zager E, Kumar MA. Safety and Feasibility of Early Mobilization in Patients with Subarachnoid Hemorrhage and External Ventricular Drain. Neurocrit Care 2019; 31 (01) 88-96
  • 43 Kumar MA, Romero FG, Dharaneeswaran K. Early mobilization in neurocritical care patients. Curr Opin Crit Care 2020; 26 (02) 147-154
  • 44 Langhorne P, Wu O, Rodgers H, Ashburn A, Bernhardt J. A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial. Health Technol Assess 2017; 21 (54) 1-120
  • 45 Hodgson CL, Stiller K, Needham DM. et al. Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults. Crit Care 2014; 18 (06) 658
  • 46 Conceição TMAD, Gonzáles AI, Figueiredo FCXS, Vieira DSR, Bündchen DC. Safety criteria to start early mobilization in intensive care units. Systematic review. Rev Bras Ter Intensiva 2017; 29 (04) 509-519
  • 47 Sandset EC, Anderson CS, Bath PM. et al. European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage. Eur Stroke J 2021; 6 (02) II
  • 48 Mead GE, Sposato LA, Sampaio Silva G. et al. A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization. Int J Stroke 2023; 18 (05) 499-531
  • 49 Graettinger WF, Lipson JL, Cheung DG, Weber MA. Validation of portable noninvasive blood pressure monitoring devices: comparisons with intra-arterial and sphygmomanometer measurements. Am Heart J 1988; 116 (04) 1155-1160
  • 50 Swain SM, Lata M, Kumar S, Mondal S, Behera JK, Mondal H. A Cross-Sectional Study on the Agreement of Perfusion Indexes Measured on Different Fingers by a Portable Pulse Oximeter in Healthy Adults. Cureus 2022; 14 (05) e24853
  • 51 Louie A, Feiner JR, Bickler PE, Rhodes L, Bernstein M, Lucero J. Four Types of Pulse Oximeters Accurately Detect Hypoxia during Low Perfusion and Motion. Anesthesiology 2018; 128 (03) 520-530
  • 52 Bernhardt J, Langhorne P, Lindley RI. et al; AVERT Trial Collaboration group. Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet 2015; 386 (9988) 46-55
  • 53 Langhorne P, Collier JM, Bate PJ, Thuy MN, Bernhardt J. Very early versus delayed mobilisation after stroke. Cochrane Database Syst Rev 2018; 10 (10) CD006187
  • 54 Directorate General of Health Services - Ministry of Health and Family Welfare. Guidelines for prevention and management of stroke. Natl Program Prev Control Cancer, Diabetes, Cardiovasc Dis Stroke Guidel, https://main.mohfw.gov.in/sites/default/files/GuidelinesforPreventionandManagmentofStroke.pdf (2019, accessed 07 November 2023)
  • 55 Bernhardt J, Churilov L, Ellery F. et al; AVERT Collaboration Group. Prespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT). Neurology 2016; 86 (23) 2138-2145
  • 56 Dutch Society for Neurology. Herseninfarct en hersenbloeding, https://richtlijnendatabase.nl/richtlijn/herseninfarct_en_hersenbloeding/revalidatie_na_herseninfarct_-bloeding.html#verantwoording (2017, accessed 7 November 2023)
  • 57 Bernhardt J, Churilov L, Dewey H. et al; AVERT DOSE Trialist Collaboration. A phase III, multi-arm multi-stage covariate-adjusted response-adaptive randomized trial to determine optimal early mobility training after stroke (AVERT DOSE). Int J Stroke 2023; 18 (06) 745-750
  • 58 Jones TA. Motor compensation and its effects on neural reorganization after stroke. Nat Rev Neurosci 2017; 18 (05) 267-280
  • 59 Cormican A, Hirani SP, McKeown E. Healthcare professionals' perceived barriers and facilitators of implementing clinical practice guidelines for stroke rehabilitation: A systematic review. Clin Rehabil 2023; 37 (05) 701-712
  • 60 Associação Brasil AVC. Ombro doloroso após AVC. http://abavc.org.br/wp-content/uploads/2021/12/ABAVC-Folder-Ombro-Doloroso.pdf , (2022, accessed 7 November 2023)
  • 61 Anderson CS, Olavarría VV. Head Positioning in Acute Stroke: Down but Not Out. Stroke 2019; 50 (01) 224-228
  • 62 Anderson CS, Arima H, Lavados P. et al; HeadPoST Investigators and Coordinators. Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke. N Engl J Med 2017; 376 (25) 2437-2447
  • 63 Ministério da Saúde (Brasil). Portaria n°. 665, de 12 de abril de 2012. Dispõe sobre os critérios de habilitação dos estabelecimentos hospitalares como Centro de Atendimento de Urgência aos Pacientes com Acidente Vascular Cerebral (AVC), no âmbito do Sistema Único de Saúde (SUS), institui o respectivo incentivo financeiro e aprova a Linha de Cuidados em AVC.
  • 64 Ministério da Saúde (Brasil). Portaria n° 800, de 17 de junho de 2015. Altera, acresce e revoga dispositivos da Portaria n° 665/GM/MS, de 12 de abril de 2012, que dispõe sobre os critérios de habilitação dos estabelecimentos hospitalares como Centro de Atendimento de Urgência aos Pacientes com Acidente Vascular Cerebral (AVC), no âmbito do Sistema Único de Saúde (SUS), institui o respectivo incentivo financeiro e aprova a Linha de Cuidados em AVC.
  • 65 Conselho Federal de Fisioterapia e Terapia Ocupacional (Brasil). Resolução COFFITO N° 444 de 26 de abril de 2014. Altera a Resolução COFFITO n° 387/2011, que fixa e estabelece os Parâmetros Assistenciais Fisioterapêuticos nas diversas modalidades prestadas pelo fisioterapeuta.
  • 66 Murayama LHV, Filho PTH, Winckler FC. et al. Caregiver burden, hopelessness, and anxiety: Association between sociodemographic and clinical profiles of patients with stroke. J Stroke Cerebrovasc Dis 2024; 33 (11) 107905
  • 67 Crocker TF, Brown L, Lam N, Wray F, Knapp P, Forster A. Information provision for stroke survivors and their carers. Cochrane Database Syst Rev 2021; 11 (11) CD001919
  • 68 Jammal M, Kolt GS, Liu KPY, Guagliano JM, Dennaoui N, George ES. A systematic review and meta-analysis of randomized controlled trials to reduce burden, stress, and strain in informal stroke caregivers. Clin Rehabil 2024; 38 (11) 1429-1445
  • 69 Mountain A, Patrice Lindsay M, Teasell R. et al. Canadian Stroke Best Practice Recommendations: Rehabilitation, Recovery, and Community Participation following Stroke. Part Two: Transitions and Community Participation Following Stroke. Int J Stroke 2020; 15 (07) 789-806
  • 70 Martins SC, Pontes-Neto OM, Alves CV. et al; Brazilian Stroke Network. Past, present, and future of stroke in middle-income countries: the Brazilian experience. Int J Stroke 2013; 8 (Suppl A100): 106-111