PDF herunterladen
Open Access
CC BY-NC-ND 4.0 · Indian J Radiol Imaging
DOI: 10.1055/s-0045-1814136
Letter to the Editor

Beyond Protons (1H1): The Era of Multinuclear Magnetic Resonance Imaging

Autor*innen

  • Prithvijit Chakraborty 

    1   Department of Radiology and Interventional Radiology, Apollo Multispeciality Hospitals, Kolkata, India
Weitere Informationen
Auch verfügbar auf
  Lizenzen und Reprints

Sir,

Since its inception, clinical magnetic resonance imaging (MRI) has almost exclusively relied on proton (1H) signal acquisition, owing to the high natural abundance and sensitivity of hydrogen in biological tissues. However, other nuclei—collectively termed X-nuclei—possess unique biochemical and physiologic signatures that can be directly interrogated by MRI, providing information inaccessible to conventional proton-based sequences. Recent technological advances in hardware, pulse sequence design, and hyperpolarization techniques are catalyzing the transition of multinuclear MRI from a research tool to targeted clinical applications.

Note

Multinuclear MRI is transitioning from niche research to clinically impactful imaging, offering unique physiologic and metabolic insights that complement conventional proton MRI in precision medicine.




Publikationsverlauf

Artikel online veröffentlicht:
12. Januar 2026

© 2026. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India