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Synthesis 1985; 1985(9): 817-845
DOI: 10.1055/s-1985-31361
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Use of Organosilicon Reagents as Protective Groups in Organic Synthesis

M. Lalonde* , T. H. Chan
  • *Department of Chemistry, McGill University, Montreal, Quebec, Canada H3A 2K6
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Publication Date:
27 September 2002 (online)

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Recent developments in the use of organosilicon reagents for the protection of organic functional groups involving hetero atoms are discussed. Conditions of protection and deprotection are described as well as the selectivity of the reagents. 1. Protection for the Hydroxy Group 2. Protection for 1,2- and 1,3-Diols 3. Protection for the Carbonyl Group 4. Protection for the Carboxyl Group 5. Protection for the Amino Group 6. Protection for the Sulfur Atom 7. Protection for the Phosphorus Atom 8. Addendum 9. Conclusions