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Synthesis 1986; 1986(1): 52-54
DOI: 10.1055/s-1986-31474
DOI: 10.1055/s-1986-31474
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Phase-Transfer Esterification of the Alkali Metal Salts of Cephalosporins and Penicillins
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Publikationsdatum:
20. August 2002 (online)
Cephalosporins and penicillins can be converted into their alkyl esters in high yields by reaction of their solid sodium or potassium salts with alkyl bromides in acetonitrile in the presence of crown ethers as phase-transfer catalysts.