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Synthesis 1986; 1986(1): 74-75
DOI: 10.1055/s-1986-31484
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Nitriles in Heterocyclic Synthesis. A Novel Synthesis of 4-Phenacylpyrazole and Pyrrolo[2,3-c]pyrazole Derivatives

Fathy Mohamed Abdelrazek* , Ayman Wahba Erian, Khalid Mohamed Hassan Hilmy
  • *Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt
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Publication Date:
20 August 2002 (online)

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3,5-Diamino-4-phenacyclpyrazoles are prepared by reaction of phenacylmalononitrile with hydrazine or phenylhydrazine. Further reaction of the 3,5-diamino-4-phenacylpyrazoles with trichloroacetonitrile provides a novel synthesis of 1,6-dihydropyrrolo[2,3-c]pyrazoles.