Synthesis 1986; 1986(5): 416-417
DOI: 10.1055/s-1986-31659
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Cyclization of 4-Hydroxy-(E)-2-alkenoic Esters: Simple Synthesis of Butenolides

Rikuhei Tanikaga* , Hiroshi Yamashita, Aritsune Kaji
  • *Department of Chemistry, Faculty of Science, Kyoto University, Sakyo-ku, Kyoto 606, Japan
Further Information

Publication History

Publication Date:
27 September 2002 (online)

Simple treatment of 4-hydroxy-(E)-2-alkenoic esters with benzenethiol leads to cyclization to give 3-phenylthio-4-alkanolides, which are easily converted into 3-phenylthio-2-alken-4-olides and 2-alken-4-olides (Δα,β-butenolides).