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Synthesis 1986; 1986(10): 842-843
DOI: 10.1055/s-1986-31798
DOI: 10.1055/s-1986-31798
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A Convenient Method for the Preparation of Bicyclo[3.3.0]oct-1-en-3-one
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Publication History
Publication Date:
20 August 2002 (online)
An efficient synthesis of bicyclo[3.3.0]oct-1-en-3-one (1) is reported which utilizes an intramolecular Horner-Emmons reaction. This reaction proceeds under phase transfer conditions and affords the bicyclic enone in good yields on a reasonably large scale.