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Synthesis 1986; 1986(12): 1024-1026
DOI: 10.1055/s-1986-31858
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Facile and Inexpensive Synthesis of 4-Oxoalkanoic Acids from Primary Nitroalkanes and Acrolein

Roberto Ballini* , Marino Petrini
  • *Dipartimento di Scienze Chimiche, Via S. Agostino, 1, I-62032 Camerino, Italy
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Publication Date:
12 September 2002 (online)

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4-Oxoalkanoic acids, useful organic compounds, are easily prepared by conjugate addition of primary aliphatic nitro compounds to acrolein on alumina surface, in the absence of a solvent, and subsequent oxidation with hydrogen peroxide/potassium carbonate.