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Synthesis 1987; 1987(2): 204-206
DOI: 10.1055/s-1987-27893
DOI: 10.1055/s-1987-27893
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Application of the Intramolecular α-Amidoalkylation Reaction for the Synthesis of 2-Arylsulfonyl-1,2,3,4-tetrahydroisoquinolines
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Publication History
Publication Date:
12 September 2002 (online)
The adducts of azomethines and sulfonyl chlorides (Method A) as well as hydroxymethylated sulfonamides (Method B) are used for the synthesis of 2-arylsulfonyl-1,2,3,4-tetrahydroisoquinolines 4a-q.