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Synthesis 1987; 1987(3): 272-274
DOI: 10.1055/s-1987-27913
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Synthesis of 2-Amino-3-ethoxycarbonylpyrroles

Emilio Toja* , Adele Depaoli, Giorgio Tuan, Jurgen Kettenring
  • *Lepetit Research Center, Via Durando 38, 20158 Milano, Italy
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Publikationsdatum:
12. September 2002 (online)

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Condensation of ethoxycarbonylacetamidine with α-bromoketones affords a versatile route to 2-amino-3-ethoxycarbonylpyrroles. Selective N-methylation is achieved under phase-transfer conditions.