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Synthesis 1987; 1987(7): 647-648
DOI: 10.1055/s-1987-28035
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Reduction of Symmetric and Mixed Anhydrides of Carboxylic Acids by Sodium Borohydride with Dropwise Addition of Methanol

Kenso Soai* , Shuji Yokoyama, Katsuko Mochida
  • *Department of Applied Chemistry, Faculty of Science, Science University of Tokyo, Shinjuku, Tokyo 162, Japan
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Publikationsdatum:
20. August 2002 (online)

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Symmetric and mixed anhydrides of carboxylic acids are reduced in high yields with sodium borohydride in tetrahydrofuran with dropwise addition of methanol.