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Synthesis 1987; 1987(12): 1138-1139
DOI: 10.1055/s-1987-28202
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An Unusual and Simple One-Pot Synthesis of Thiazolo[5,4-d]-thiazoles

Ricardo Bossio* , Stefano Marcaccini, Roberto Pepino, Tomas Torroba, Giovanni Valle
  • *CNR, Centro di studio sulla chimica e la struttura dei composti eterociclici e loro applicazioni, Dipartimento di Chimica Organica "U. Schiff", Università di Firenze, via G. Capponi 9, I-50121 Firenze, Italy
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Publication Date:
20 August 2002 (online)

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The reaction between ethyl isocyanoacetate and dichlorodisulfane in the presence of triethylamine afforded diethyl thiazolo[5,4-d]thiazole-2,5-dicarboxylate. This reaction provides a useful method for the synthesis of the above ring system.