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Synthesis 1988; 1988(2): 148-149
DOI: 10.1055/s-1988-27497
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Synthesis of New Bis(1-hydroxy-9-oxo-9,10-dihydro-3-acridinyl) Alkanedioates

R. Vidal* , J. -P. Galy, E. -J. Vincent, J. Barbe
  • *Laboratoire de Chimie Organique Physique, UFR de Chimie, rue Henri-Poincaré, F-13397 Marseille Cedex 13, France
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Publication Date:
20 August 2002 (online)

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Acylation of 1,3-dihydroxy-9-acridone can be performed by using thallous ethoxide as intermediary. Accordingly only the monoacylated derivative is obtained. Some bis-(1-hydroxy-9-oxo-9,10-dihydro-3-acridinyl) alkanedioates were prepared by this method as potential DNA intercalating agents.