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Synthesis 1988; 1988(3): 244-246
DOI: 10.1055/s-1988-27531
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A Simple, One-Pot Synthesis of Novel 1H, 3H-Thiazolo-[3,4-a]benzimidazoles

Alba Chimirri* , Silvana Grasso, Pietro Monforte, Giovanni Romeo, Maria Zappalà
  • *Dipartimento Farmaco-Chimico, Università, Viale SS. Annuziata, I-98100 Messina, Italy
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Publication Date:
20 August 2002 (online)

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A novel one-pot synthesis of 1H,3H-thiazolo[3,4-a]benzimidazoles has been developed by the reaction between o-phenylenediamine, 2-mercaptocarboxylic acid and a variety of carbonyl compounds in refluxing benzene.