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Synthesis 1988; 1988(7): 556-557
DOI: 10.1055/s-1988-27638
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A Novel Route to Methyl 3-(3,4-Disubstituted 5-alkylthio/amino-2-thienyl) propenoates

A. Datta* , H. Ila, H. Junjappa
  • *Department of Chemistry, North-Eastern Hill University, Shillong 793 003, Meghalaya, India
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Publikationsdatum:
18. September 2002 (online)

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The 3-oxodithioesters 1 and 3-oxothioamides 6 are shown to undergo base catalyzed S-alkylation with methyl 4-bromocrotonate followed by intramolecular condensation to give the corresponding methyl 3-(3,4-disubstituted 5-alkylthio/amino-2-thienyl) propenoates 5 and 7 in good yields.