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Synthesis 1988; 1988(7): 560-562
DOI: 10.1055/s-1988-27640
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Crown Ether Catalyzed O-Alkylation of Carbohydrates and Nucleosides

Michel Bessodes* , Jila Shamsazar, Kostas Antonakis
  • *Institut de Recherches Scientifiques sur le Cancer, BP8, F-94802 Villejuif, France
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Publication Date:
18 September 2002 (online)

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Carbohydrate derivatives as well as nucleosides are readily alkylated with different alkyl halides in tetrahydrofuran using potassium hydroxide in the presence of crown ether.