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Synthesis 1989; 1989(1): 57-59
DOI: 10.1055/s-1989-27152
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A New Method for the Generation of Nitrile Oxides and Its Application to the Synthesis of 2-Isoxazolines

Alfred Hassner* , K. M. Lokanatha Rai
  • *Department of Chemistry, Bar-Ilan University, Ramat-Gan 52100, Israel
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Publication Date:
27 September 2002 (online)

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Reaction of aldoximes with choramine-T leads to formation of nitrile oxides which can react in situ intra- or intermolecularly with olefinic compounds to produce isoxazolines in good yield.