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Synthesis 1989; 1989(4): 307-309
DOI: 10.1055/s-1989-27236
DOI: 10.1055/s-1989-27236
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A Direct Synthesis of N,N′-Bis(2-hydroxybenzylidene)-1,1-diaminoalkanes by a Three-Component Reaction
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Publication History
Publication Date:
17 September 2002 (online)
The direct synthesis of new double Schiff bases with an alkane-1,1-diamine unit is achieved in good yields through a three-component reaction of salicylaldehyde or 5-bromosalicylaldehyde, aliphatic aldehydes, and ammonium acetate or aqueous ammonia in methanol.