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Synthesis 1989; 1989(4): 317-320
DOI: 10.1055/s-1989-27241
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Synthesis of 7-Substituted 5-Oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic Acids, 2-Substituted 4-Oxo-4H-pyrido [1,2-a]pyrimidine-3-carboxylic Acids, and 2,6-Disubstituted 4-Quinolones from Meldrum's Acid Derivatives

Fang-Chen Ye* , Bang-Chi Chen, Xian Huang
  • *Department of Chemistry, Hangzhou University, Hangzhou, People's Republic of China
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Publication Date:
17 September 2002 (online)

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The title compounds are prepared from the Meldrum acid derivatives 5-[bis(methylthio)methylene]-, 5-(1-methylthioalkylidene)- and 5-(α-methylthiobenzylidene)-2,2-dimethyl-4,6-dioxo-1,3-dioxanes by reaction with 2-aminothiazole, 2-aminopyridine, or anilines, respectively.