Download PDF
Synthesis 1989; 1989(4): 334-337
DOI: 10.1055/s-1989-27248
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

(Trimethylsilyl)ethoxyacetylene. An Effective Reagent for Mild Dehydrative Condensation of Carboxylic Acids and H-Acidic Materials

Yasuyuki Kita* , Shuji Akai, Miki Yamamoto, Miyako Taniguchi, Yasumitsu Tamura
  • *Faculty of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565, Japan
Further Information

Publication History

Publication Date:
17 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

(Trimethylsilyl)ethoxyacetylene, a stable and easy to handle dehydrating reagent, is quite effective for the title condensation to prepare esterlactone-, lactam-, and peptide-linkages under mild conditions.