Synthesis 1989; 1989(5): 394-395
DOI: 10.1055/s-1989-27263
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Ein bequemes Eintopfverfahren zur Synthese von 1,2-Benzisothiazol-1,1-dioxiden

D. Hellwinkel* , R. Karle
  • *Organisch-Chemisches Institut der Universitát Heidelberg, Im Neuenheimer Feld 270, D-6900 Heidelberg, Federal Republic of Germany
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Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

A Facile One-Pot Procedure for the Synthesis of 1,2-Benzisothiazole 1,1-Dioxides ortho-Lithiated N,N-diphenylbenzenesulfonamides 6 react with aromatic nitriles and N,N-dimethylcarbamonitrile, respectively, to give directly the corresponding 3-substituted 1,2-benzisothiazole-1,1-dioxides 8a-f. Other cyano compounds only transfer the cyano group or its ligands to generate the o-substituted benzenesulfonamides 9a-d.