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Synthesis 1989; 1989(5): 396-397
DOI: 10.1055/s-1989-27264
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Reaction of 3-Hydroxyisoindolin-1-ones with Lawesson Reagent. Synthesis of Isoindoline-1-thiones

Takehiko Nishio* , Norikazu Okuda, Yo-ichi Mori, Choji Kashima
  • *Department of Chemistry, University of Tsukuba, Tennodai, Tsukubashi, Ibaraki 305, Japan
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Publication Date:
17 September 2002 (online)

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Treatment of 3-hydroxyisoindolin-1-ones 1 with Lawesson reagent gave isoindoline-1-thiones 2, by direct thionation and reductive elimination of hydroxy group, in good yields.