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Synthesis 1989; 1989(6): 456-457
DOI: 10.1055/s-1989-27288
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A Facile and Concise Synthesis of 2-Alkyl- and 2-Aryl-4-oxo- 4H thiopyrano[2,3-b]pyridines

Axel Couture* , Pierre Grandclaudon, Eric Huguerre
  • *Laboratoire de Chimie Organique Physique, U.A. C.N.R.S. No 351, Université des Sciences & Techniques de Lille Flandres Artois, F-59655 Villeneuve d'Ascq Cedex, France
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Publication Date:
17 September 2002 (online)

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2-Alkyl- and 2-aryl-4-oxo-4H-thiopyrano[2,3-b]pyridine can be conveniently prepared by reacting the appropriate aromatic and aliphatic O-ethyl thiocarboxylates with the sodium derivative of various alkyl 3-(2-bromopyridyl) ketones.