Synthesis 1989; 1989(12): 898-901
DOI: 10.1055/s-1989-27425
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Stereocontrolled Total Synthesis of (5Z,8Z,10E,12R,14Z)-12-Hydroxy-5,8,10,14-icosatetraenoic Acid [(12R)-HETE]

K. C. Nicolaou* , J. Y. Ramphal, Y. Abe
  • *Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA
Further Information

Publication History

Publication Date:
02 May 2002 (online)

A stereocontrolled convergent synthesis of (12R)-HETE (1) by palladium (0)/thallium hydroxide mediated coupling of vinylborane 2 with the vinyl iodide 3 is reported.