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Synlett 1990; 1990(3): 159-160
DOI: 10.1055/s-1990-21020
DOI: 10.1055/s-1990-21020
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Microbial Oxidation of Chloroaromatics in the Enantioselective Synthesis of Carbohydrates: L-Ribonic γ-Lactone
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Publication History
Publication Date:
08 March 2002 (online)
L-Ribonic γ-Lactone 2 has been prepared in five steps from chlorobenzene. The key reaction is the microbial oxidation of chlorobenzene by Pseudomonas putida to afford chiral cyclohexadiendiol 6.