Download PDF
Synlett 1990; 1990(5): 265-266
DOI: 10.1055/s-1990-21058
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Chiral Polyfunctional γ-Lactones via an Intramolecular 1,6 Michael-Type Addition

Mohammed Laabassi* , René Grée
  • *Groupe de Recherche de Physicochimie Structurale, CNRS URA D0704, Université de Rennes I, Avenue du Gal Leclerc, F-35042 Rennes-Beaulieu, France
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A short and efficient synthesis of chiral and functionalized γ-lactones 5 and 6 is described. It takes advantage of the highly stereoselective 1,6 Michael-type addition of a malonate anion to an electrophilic diene.