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Synlett 1990; 1990(8): 455-456
DOI: 10.1055/s-1990-21124
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A Total Synthesis of Neopatulin

Mandy Bennett* , G. Bryon Gill, Gerald Pattenden, Anthony J. Shuker
  • *Department of Chemistry, The University, Nottingham NG7 2RD, England
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Publication History

Publication Date:
08 March 2002 (online)

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A total synthesis of neopatulin (1; 6-hydroxy-4H-furo [3,2-c]pyran-2(6H)-one) a redox isomer of patulin (2; 4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one), which is produced by Penicillium and Aspergillus spp., is described starting from either D-lyxose or furfuryl alcohol.