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Synthesis 1990; 1990(6): 499-501
DOI: 10.1055/s-1990-26919
DOI: 10.1055/s-1990-26919
paper
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Chemistry of 3-Hydroxypyridine Part 2: Synthesis of 5,6-Dihalo-3-hydroxypyridines
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Publikationsdatum:
17. September 2002 (online)
The multistep synthesis of hitherto unknown 5,6-dihalo-3-hydroxypyridines starting from commercially available 2-hydroxy-5-nitropyridine is described. The suitability of cheap 2-aminomethylfuran (furfurylamine) for the preparation of the title compounds in a novel two step process was also explored.