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Synthesis 1990; 1990(8): 689-690
DOI: 10.1055/s-1990-26982
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Rapid, High-Yield Oxidation of Hantzsch-Type 1,4-Dihydropyridines with Ceric Ammonium Nitrate

Jürg R. Pfister*
  • *Institute of Organic Chemistry, Syntex Research, Palo Alto, California CA 94304, USA
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Publication Date:
17 September 2002 (online)

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4-Aryl-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylates, Hantzsch-type 1,4-dihydropyridines, are rapidly oxidized to the corresponding pyridine derivatives in excellent yields using two equivalents of ceric ammonium nitrate.