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Synthesis 1990; 1990(10): 911-914
DOI: 10.1055/s-1990-27051
DOI: 10.1055/s-1990-27051
paper
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A Convenient and General Synthesis of 2-Aryl- and 2-Pyridyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazines
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Publication History
Publication Date:
17 September 2002 (online)
The reaction of bis(2-aminophenyl) disulphide 1 with methyl or ethyl aryl- or pyridylacetates and sodium hydride gives the title compounds in good yield and high purity. The reaction is general, the starting materials easily available and the workup is simple and rapid