Synthesis 1990; 1990(10): 911-914
DOI: 10.1055/s-1990-27051
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A Convenient and General Synthesis of 2-Aryl- and 2-Pyridyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazines

Niels Jacobsen* , Hans Kolind-Andersen
  • *Research Department, A/S Cheminova, P.O. Box 9, DK-7620 Lemvig, Denmark
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Publication History

Publication Date:
17 September 2002 (online)

The reaction of bis(2-aminophenyl) disulphide 1 with methyl or ethyl aryl- or pyridylacetates and sodium hydride gives the title compounds in good yield and high purity. The reaction is general, the starting materials easily available and the workup is simple and rapid