Download PDF
Synlett 1991; 1991(11): 831-832
DOI: 10.1055/s-1991-20895
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Total Synthesis of Cyclophellitol from L-Quebrachitol

Takahiko Akiyama* , Masatoshi Ohnari, Hiroaki Shima, Shoichiro Ozaki
  • *Department of Applied Chemistry, Faculty of Engineering, Ehime University, Bunkyo-cho, Matsuyama 790, Japan
Further Information

Publication History

Publication Date:
07 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Cyclophellitol [1L-(1,3/2,4,5,6)-4,5-epoxy-6-(hydroxy-methyl)cyclohexane-1,2,3-triol] , a ß-glucosidase inhibitor, has been synthesized enantiospecifically from a naturally abundant cyclitol, L-quebrachitol (1L-2-O-methyl-chiro-inositol), via a Peterson olefination and an aluminum trichloride-tetrabutylammonium iodide mediated demethylation.