PDF herunterladen
Synthesis 1991; 1991(3): 211-213
DOI: 10.1055/s-1991-26422
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Convenient Synthesis of 8-Alkyl- and 8-Alkylthio-2-(4-pyridyl)adenines

Balder Singh* , George Y. Lesher
  • *Department of Medicinal Chemistry, Sterling Research Group, Rensselaer, NY 12144, USA
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Several 8-alkyl-2-(4-pyridyl)adenine analogs 5 were prepared by reacting 4,5,6-triaminopyrimidine 4 with acid anhydrides, acids or dimethylformamide dimethyl acetal. 8-Mercapto-2-(4-pyridyl)-adenine (6), prepared by treating 4 with O-potassium O-ethyl dithiocarbonate was alkylated to give 8-alkylthioadenine derivatives 7.