Download PDF
Synthesis 1991; 1991(3): 232-233
DOI: 10.1055/s-1991-26430
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Palladium-Catalyzed Coupling of (1,3-Butadiynyl)amines with Aryl and Vinyl Iodides

Achim Löffler* , Gerhard Himbert
  • *Fachbereich Chemie der Universität Kaiserslautern, Postfach 3049, D-6750 Kaiserslautern, Germany
Further Information

Publication History

Publication Date:
17 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

4-Aryl, 4-heteroaryl- and 4-vinyl substituted (1,3-butadiynyl)-amines 7 and 8 are prepared in a one-pot synthesis by the successive treatment of the (3,4,4-trichloro-3-buten-1-ynyl)amines 1 with two equivalents of butyllithium and zinc chloride and by the palladium-catalyzed cross-coupling of the resulting aminobutadiynylzinc chlorides 4 with alkenyl, aryl and heteroaryl iodides, respectively.